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Target
Cyclin-dependent kinase 2
Ligand
BDBM91758
Substrate
n/a
Meas. Tech.
OctetRed_Method1
Kd
>100000±n/a nM
Citation
 D3R, DD CSAR CDK2 Kinase D3R 220:0 (2015) [PubMed] 
Target
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Inhibitor
Name:
BDBM91758
Synonyms:
CS184
Type:
n/a
Emp. Form.:
C19H21N5O2S
Mol. Mass.:
383.467
SMILES:
COc1ccccc1CNC(=O)CSc1nnnn1-c1c(C)cccc1C |(9.26,.77,;9.26,-.77,;7.93,-1.54,;6.59,-.77,;5.26,-1.54,;5.26,-3.08,;6.59,-3.85,;7.93,-3.08,;9.26,-3.85,;10.6,-3.08,;11.93,-3.85,;11.93,-5.39,;13.26,-3.08,;14.6,-3.85,;15.93,-3.08,;16.09,-1.55,;17.6,-1.23,;18.37,-2.56,;17.34,-3.7,;17.66,-5.21,;16.51,-6.24,;15.05,-5.77,;16.83,-7.75,;18.3,-8.22,;19.44,-7.19,;19.12,-5.69,;20.27,-4.66,)|
Structure:
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