Reaction Details Report a problem with these data
Target
Serine/threonine-protein kinase Chk1 [2-280]
Ligand
BDBM91932
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
2190±n/a nM
Citation
 D3R, DD Abbott CHK1 Kinase D3R 221:0 (2015) [PubMed] 
Target
Name:
Serine/threonine-protein kinase Chk1 [2-280]
Synonyms:
CHEK1 | CHK1 | CHK1_HUMAN | CHK1_Kinase
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
O14757[2-280]
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
  
Inhibitor
Name:
BDBM91932
Synonyms:
Chk1_64
Type:
n/a
Emp. Form.:
C21H15N3O5
Mol. Mass.:
389.3609
SMILES:
OC(=O)Cc1ccc2Nc3cc(ccc3C(=O)Nc2c1)-c1cccc(c1)[N+]([O-])=O
Structure:
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