Reaction Details Report a problem with these data
Target
L-lactate dehydrogenase B chain
Ligand
BDBM23222
Substrate
n/a
Meas. Tech.
LDH Activity Assay
pH
7.4±n/a
IC50
60000±n/a nM
Comments
extracted
Citation
 Rodríguez-Páez, L; Chena-Taboada, MA; Cabrera-Hernández, A; Cordero-Martínez, J; Wong, C Oxamic acid analogues as LDH-C4-specific competitive inhibitors. J Enzyme Inhib Med Chem 26:579-86 (2011) [PubMed]  Article 
Target
Name:
L-lactate dehydrogenase B chain
Synonyms:
L-lactate:NAD+ oxidoreductase B (LDH-B4) | LDHB_MOUSE | Ldh-2 | Ldh2 | Ldhb
Type:
Enzyme
Mol. Mass.:
36569.37
Organism:
Mus musculus (Mouse)
Description:
P16125
Residue:
334
Sequence:
MATLKEKLIASVADDEAAVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCTIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLRKSADTLWDIQKDLKDL
  
Inhibitor
Name:
BDBM23222
Synonyms:
Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Acid | carbamoylformic acid
Type:
Small organic molecule
Emp. Form.:
C2H3NO3
Mol. Mass.:
89.0501
SMILES:
NC(=O)C(O)=O
Structure:
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