Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50350465
Substrate
n/a
Meas. Tech.
Esterase Activity Assay
pH
7.4±0
Temperature
298.15±0 K
Ki
8.30e+4±n/a nM
IC50
5.68e+4±n/a nM
Citation
 Cankaya, M; Aktas, M; Kuzucu, M; Gül, Ä°; Coban, TA Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study. J Enzyme Inhib Med Chem 27:641-5 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50350465
Synonyms:
AMPICILLIN | AY-6108 | Amcill | Aminobenzylpenicillin | Ampicillin sulfate
Type:
Small organic molecule
Emp. Form.:
C16H19N3O4S
Mol. Mass.:
349.405
SMILES:
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O |r|
Structure:
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