Assay Method Information

Assay Name:  ChEMBL_1986128 (CHEMBL4619534)
Description:  Inhibition of recombinant full-length C-terminal His6-tagged Escherichia coli DNA gyrase AB supercoiling activity using relaxed DNA as substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs in presence of ATP by size exclusion HPLC analysis
Affinity data for this assay
 

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