Assay Method Information | |
| ChEMBL_951498 (CHEMBL2350651) |
Description: | Competitive inhibition of human recombinant DOT1L (1 to 472 amino acid residues) expressed in Escherichia coli BL21 (DE3) using [3H]-SAM assessed as inhibition of nucleosome methylation incubated for 10 mins prior to substrate addition measured after 30 mins by scintillation counting analysis |
Affinity data for this assay | |
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