Compile Data Set for Download or QSAR
Report error Found 125 of affinity data for UniProtKB/TrEMBL: A5A4K8
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268430((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421355(CHEMBL289955)
Affinity DataIC50: 1.80nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268433((S)-2-((S)-2-amino-N-methyl-3-phenylpropanamido)-N...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421358(CHEMBL45141)
Affinity DataIC50: 1.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421357(CHEMBL297168)
Affinity DataIC50: 2.30nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421355(CHEMBL289955)
Affinity DataIC50: 2.5nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421354(CHEMBL26966)
Affinity DataIC50: 3.20nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421354(CHEMBL26966)
Affinity DataIC50: 3.20nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421356(CHEMBL43313)
Affinity DataIC50: 3.5nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421356(CHEMBL43313)
Affinity DataIC50: 3.80nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50: 3.80nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50: 3.80nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421357(CHEMBL297168)
Affinity DataIC50: 3.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268432((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50: 6nMAssay Description:Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268377((S)-2-amino-N-((S)-1-((S)-1-amino-3-(3-tert-butyl-...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50: 6.5nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421349(CHEMBL265495)
Affinity DataIC50: 6.5nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344952((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as increase of muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108830(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)
Affinity DataIC50: 7nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344952((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344952((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50: 7.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421351(CHEMBL27424)
Affinity DataIC50: 7.90nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50: 8.90nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50: 8.90nMAssay Description:In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50: 8.90nMpH: 2.5 T: 2°CAssay Description:Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421350(CHEMBL27419)
Affinity DataIC50: 9.10nMAssay Description:In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article

TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108832(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268376((S)-2-amino-N-((S)-2-((S)-1-amino-3-(3-tert-butyl-...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268378((S)-2-amino-N-((3S,6S)-3-(3-tert-butyl-4-hydroxybe...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344950(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108833(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)
Affinity DataIC50: 17nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344948((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268431((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299521(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268429((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299520(N-cyclobutyl-2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299519(N-cyclopropyl-2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S...)
Affinity DataEC50:  31nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108830(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)
Affinity DataIC50: 33nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108829(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)
Affinity DataIC50: 33nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344949(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50268428((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299499(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299518(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299518(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299517(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299517(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMotilin receptor(Rabbit)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50108829(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)
Affinity DataIC50: 59nMAssay Description:Inhibition of the motilin receptor (MTL-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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