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Report error Found 212 of affinity data for UniProtKB/TrEMBL: B0B3F0
TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM123410(US8754106, 82 | US8754106, 91 | US8741926, 82)
Affinity DataKi:  0.0500nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM123413(US8754106, 94 | US8741926, 94)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM124106(US8754106, 56)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM123415(US8754106, 95 | US8741926, 95)
Affinity DataKi:  0.100nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM124107(US8754105, 23)
Affinity DataKi:  0.200nM ΔG°:  -56.3kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM123414(US8754106, 48 | US8741926, 48)
Affinity DataKi:  0.25nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM123412(US8754106, 57 | US8741926, 57)
Affinity DataKi:  0.300nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110357(US8613914, 125 | US9206232, 129)
Affinity DataIC50: 0.300nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110396(US8613914, 170 | US9206232, 170)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM50336504((2R,3aR,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-...)
Affinity DataKi:  0.5nMAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110400(US8613914, 174 | US9206232, 174)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110393(US8613914, 167 | US9206232, 167)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110273(US8613914, 41 | US9206232, 41)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110309(US8613914, 77)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110388(US8613914, 162 | US9206232, 162)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110280(US8613914, 48 | US9206232, 48)
Affinity DataIC50: 0.900nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110397(US8613914, 171 | US9206232, 171)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110383(US8613914, 157 | US9206232, 157)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110277(US8613914, 45 | US9206232, 45)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110264(US8613914, 32 | US9206232, 32)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110294(US8613914, 62 | US9206232, 62)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110378(US8613914, 152 | US9206232, 152)
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110295(US8613914, 63 | US9206232, 63)
Affinity DataIC50: 1.20nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110382(US8613914, 156 | US9206232, 156)
Affinity DataIC50: 1.30nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110287(US8613914, 55 | US9206232, 55)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110354(US8613914, 122 | US9206232, 122)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110344(US8613914, 112 | US9206232, 112)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110360(US8613914, 128 | US9206232, 128)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110395(US8613914, 169 | US9206232, 169)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110356(US8613914, 124 | US9206232, 124)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110375(US8613914, 147 | US9206232, 147)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110326(US8613914, 94 | US9206232, 94)
Affinity DataIC50: 1.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110285(US8613914, 53 | US9206232, 53)
Affinity DataIC50: 1.70nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110379(US8613914, 153 | US9206232, 153)
Affinity DataIC50: 1.80nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110315(US8613914, 83 | US9206232, 83)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110325(US8613914, 93 | US9206232, 93)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110260(US8613914, 28 | US9206232, 28)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110377(US8613914, 151 | US9206232, 151)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110296(US8613914, 64 | US9206232, 64)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110312(US8613914, 80)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110247(US8613914, 15 | US9206232, 15)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110278(US8613914, 46 | US9206232, 46)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110248(US8613914, 16 | US9206232, 16)
Affinity DataIC50: 2.30nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM124112(US8754105, 25)
Affinity DataKi:  2.40nM ΔG°:  -50.0kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110376(US8613914, 150 | US9206232, 150)
Affinity DataIC50: 2.40nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110333(US8613914, 101 | US9206232, 101)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110284(US8613914, 52 | US9206232, 52)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110314(US8613914, 82 | US9206232, 82)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110271(US8613914, 39 | US9206232, 39)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

TargetGenome polyprotein(Hepacivirus C)
Janssen Ireland

US Patent
LigandPNGBDBM110286(US8613914, 54 | US9206232, 54)
Affinity DataIC50: 2.5nMAssay Description:The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2014
Entry Details
US Patent

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