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Report error Found 36 of affinity data for UniProtKB/TrEMBL: E9PU00
LigandPNGBDBM776128(US12435061, Compound 1-321)
Affinity DataIC50: 5.37nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776061((2-chlorophenyl)(4-((S)-3-(3-chloropyridin-2-yloxy...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776174((5-(2-isopropylphenoxy)-2-(1-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM775793((R)-4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)pyrro...)
Affinity DataIC50: 283nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776184(US12435061, Compound 2-95)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM775798((S)-4'-fluoro-4-(3-(5-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 1.14E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50285610(CHEMBL4170268 | CBV)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
LigandPNGBDBM776180((6-chloropyridin-2-yl)(3-(2-(hydroxymethyl)-4-(2-i...)
Affinity DataIC50: 3.91E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol(C...)
Affinity DataEC50:  5.30E+3nMAssay Description:Agonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo4-AM probe based fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
LigandPNGBDBM776200(US12435061, Compound 2-80)
Affinity DataIC50: 5.52E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50463447(CHEMBL4249046)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at rat TRPV3 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM776190((4-chloropyridin-2-yl)(3-(3-(hydroxymethyl)-2'-iso...)
Affinity DataIC50: 6.97E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776191(5-chloropyridin-2-yl)(3-(2'-cyclopropyl-3-(hydroxy...)
Affinity DataIC50: 7.29E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776185((5-fluoropyridin-2-yl)(3-(3-(hydroxymethyl)-2'-iso...)
Affinity DataIC50: 7.38E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50463447(CHEMBL4249046)
Affinity DataIC50: 8.00E+3nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM776197((3-(2'-cyclopropyl-3-(hydroxymethyl)biphenyl-4-yl)...)
Affinity DataIC50: 9.24E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776175((5-fluoropyridin-2-yl)(3-(2-(hydroxymethyl)-4-(2-i...)
Affinity DataIC50: 9.65E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776194((3-(2'-ethyl-3-(hydroxymethyl)-3'-methylbiphenyl-4...)
Affinity DataIC50: 1.01E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776182(2-(1-(3-chloropicolinoyl)pyrrolidin-3-yl)-5-(2-iso...)
Affinity DataIC50: 1.04E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776179(4-(2-(hydroxymethyl)-4-(2-isopropylphenoxy)phenyl)...)
Affinity DataIC50: 1.08E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776199((3-(2'-cyclopropyl-3-(hydroxymethyl)biphenyl-4-yl)...)
Affinity DataIC50: 1.17E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776195((5-chloropyridin-2-yl)(3-(2'-ethoxy-3-(hydroxymeth...)
Affinity DataIC50: 1.23E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776173((3-chloropyridin-2-yl)(3-(2-(hydroxymethyl)-4-(2-i...)
Affinity DataIC50: 1.26E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50463445(CHEMBL4238545)
Affinity DataIC50: 1.28E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM776189((4-chloropyridin-2-yl)(3-(2'-ethyl-3-(hydroxymethy...)
Affinity DataIC50: 1.34E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776183((3-(2'-ethyl-3-(hydroxymethyl)biphenyl-4-yl)pyrrol...)
Affinity DataIC50: 1.37E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776192((3-(2'-cyclopropyl-3-(hydroxymethyl)biphenyl-4-yl)...)
Affinity DataIC50: 1.50E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776172((3-chloropyridin-2-yl)(3-(4-(2-ethylphenoxy)-2-(hy...)
Affinity DataIC50: 1.60E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776188((3-(2'-ethyl-3-(hydroxymethyl)biphenyl-4-yl)pyrrol...)
Affinity DataIC50: 1.72E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776193((3-(2'-ethyl-3-(hydroxymethyl)-4'-methylbiphenyl-4...)
Affinity DataIC50: 1.77E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776187(US12435061, Compound 2-42)
Affinity DataIC50: 1.83E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM776181((3-chloropyridin-2-yl)(3-(4-(5-ethylpyrimidin-4-yl...)
Affinity DataIC50: 3.20E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50463446(CHEMBL4244422)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463442(CHEMBL4242719)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463443(CHEMBL4241477)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463444(CHEMBL4238978)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular calcium level pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed