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Report error Found 5 of affinity data for UniProtKB/TrEMBL: O70628
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50543968(CHEMBL4636079)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse PDE9A expressed in baculovirus infected Sf9 insect cells using 3[H]-cGMP as substrate incubated for 60 mins by scintillation prox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM130503(US8822479, 37-1)
Affinity DataIC50: 55nMAssay Description:Displacement of [8-3H]-cGMP from recombinant mouse PDE9A expressed in baculovirus infected Sf9 insect cells incubated for 60 mins by scintillation pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50602398(CHEMBL5198935)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of mouse PDE9A expressed in recombinant CHO cells coexpressing soluble guanylate cyclase incubated for 6 mins by [3H]-cGMP scintillation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of mouse PDE9A expressed in recombinant CHO cells coexpressing soluble guanylate cyclase incubated for 6 mins by [3H]-cGMP scintillation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Mouse)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50602402(CHEMBL5181099)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mouse PDE9A expressed in recombinant CHO cells coexpressing soluble guanylate cyclase incubated for 6 mins by [3H]-cGMP scintillation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed