Compile Data Set for Download or QSAR
Report error Found 426 of affinity data for UniProtKB/TrEMBL: O77636
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136286BDBM50136286((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataIC50: 0.0660nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229322BDBM50229322((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227856BDBM50227856((3R,4R)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227856BDBM50227856((3R,4R)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136266BDBM50136266((3R,4S)-1-Isobutyryl-piperidine-3,4-dicarboxylic a...)
Affinity DataIC50: 0.220nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136270BDBM50136270((3R,4S)-1-Butyryl-piperidine-3,4-dicarboxylic acid...)
Affinity DataIC50: 0.260nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136285BDBM50136285((3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin...)
Affinity DataIC50: 0.280nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136261BDBM50136261((3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin...)
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136283BDBM50136283((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136275BDBM50136275((3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin...)
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136262BDBM50136262((3R,4S)-1-(1-Methyl-1H-imidazole-4-sulfonyl)-piper...)
Affinity DataIC50: 0.310nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183715BDBM50183715(N-(4-(2-(hydroxyamino)-2-oxoethyl)tetrahydro-2H-py...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183715BDBM50183715(N-(4-(2-(hydroxyamino)-2-oxoethyl)tetrahydro-2H-py...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371344BDBM50371344(CHEMBL403401)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136263BDBM50136263((3R,4S)-Piperidine-1,3,4-tricarboxylic acid 1-tert...)
Affinity DataIC50: 0.410nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136279BDBM50136279((3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin...)
Affinity DataIC50: 0.440nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136269BDBM50136269((3R,4S)-1-Cyclopropanecarbonyl-piperidine-3,4-dica...)
Affinity DataIC50: 0.450nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136268BDBM50136268((3R,4S)-1-Methanesulfonyl-piperidine-3,4-dicarboxy...)
Affinity DataIC50: 0.480nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26526BDBM26526(BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...)
Affinity DataKi:  0.560nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26526BDBM26526(BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26526BDBM26526(BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136274BDBM50136274((3R,4S)-1-(Furan-2-carbonyl)-piperidine-3,4-dicarb...)
Affinity DataIC50: 0.800nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152922BDBM50152922(N-Hydroxy-2-{1-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136273BDBM50136273((3R,4S)-1-Thiazol-2-ylmethyl-piperidine-3,4-dicarb...)
Affinity DataIC50: 0.800nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136288BDBM50136288((3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin...)
Affinity DataIC50: 0.830nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371342BDBM50371342(CHEMBL270800)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152926BDBM50152926(2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129055BDBM50129055((S)-2-Acetylamino-N-hydroxy-2-{(R)-1-[4-(2-methyl-...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26561BDBM26561((3S,4S)-3-N-hydroxy-4-N-{4-[(2-methyl-1H-indol-3-y...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152910BDBM50152910(1-Butyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benze...)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26563BDBM26563((3R,4R)-4-N-{4-[(2-ethyl-1H-indol-3-yl)methyl]benz...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152932BDBM50152932(N-Hydroxy-2-{2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26565BDBM26565((3S,4S)-3-N-hydroxy-4-N-{4-[(2-methyl-1-benzofuran...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183725BDBM50183725(N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-(methylsulfon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26526BDBM26526(BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...)
Affinity DataIC50: 1nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26568BDBM26568((3R,4R)-3-N-hydroxy-4-N-[4-({2-methylimidazo[1,2-a...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26570BDBM26570((3R,4R)-4-N-[4-({2-cyclopropylimidazo[1,2-a]pyridi...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26575BDBM26575((3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)py...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136284BDBM50136284((2S,3S)-1-Cyclopropylmethyl-piperidine-2,3-dicarbo...)
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204408BDBM50204408((3R,4R)-N-hydroxy-4-(4-((2-isopropylquinolin-4-yl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26789BDBM26789(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204404BDBM50204404((3S,4S)-tert-butyl 3-(hydroxycarbamoyl)-4-(4-((2-m...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26791BDBM26791(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-({4-[(2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129036BDBM50129036(N-(((S)-Hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quin...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26793BDBM26793(tert-butyl (3S,4S)-3-(hydroxycarbamoyl)-4-[(4-{[2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204403BDBM50204403((3R,4R)-4-(4-((2,3-dihydro-1H-cyclopenta[b]quinoli...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136271BDBM50136271((3R,4S)-1-Acetyl-piperidine-3,4-dicarboxylic acid ...)
Affinity DataIC50: 1nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26795BDBM26795(N-[(1R,2S)-2-(hydroxycarbamoyl)cyclopentyl]-4-{[2-...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152907BDBM50152907(2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152933BDBM50152933(N-Hydroxy-2-{1-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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