Compile Data Set for Download or QSAR
Report error Found 32 of affinity data for UniProtKB/TrEMBL: O77760
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461446BDBM50461446(CHEMBL4227742)
Affinity DataIC50: 230nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461446BDBM50461446(CHEMBL4227742)
Affinity DataIC50: 780nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281511BDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50: 900nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461447BDBM50461447(CHEMBL4228016)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360305BDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III | US12...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461447BDBM50461447(CHEMBL4228016)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611390BDBM50611390(CHEMBL5267472)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of african green monkey SOAT1 expressed in CHO cells assessed as reduction cholesteryl ester synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450891BDBM50450891(CHEMBL4212280)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450891BDBM50450891(CHEMBL4212280)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461448BDBM50461448(CHEMBL4227559)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281511BDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611391BDBM50611391(CHEMBL5274065)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of african green monkey SOAT1 expressed in CHO cells assessed as reduction cholesteryl ester synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50360305BDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III | US12...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461448BDBM50461448(CHEMBL4227559)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450893BDBM50450893(CHEMBL4207391)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450893BDBM50450893(CHEMBL4207391)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611389BDBM50611389(CHEMBL5272794)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of african green monkey SOAT1 expressed in CHO cells assessed as reduction cholesteryl ester synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204547BDBM50204547(CHEMBL3923673)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611392BDBM50611392(CHEMBL5284134)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of african green monkey SOAT1 expressed in CHO cells assessed as reduction cholesteryl ester synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450892BDBM50450892(CHEMBL4207917)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204553BDBM50204553(CHEMBL3971022)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450892BDBM50450892(CHEMBL4207917)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204551BDBM50204551(CHEMBL3958875)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50242257BDBM50242257(2-(1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8,8a-octahydr...)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204552BDBM50204552(CHEMBL3959948)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196069BDBM50196069(CHEMBL3965313)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204548BDBM50204548(CHEMBL3932453)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204558BDBM50204558(CHEMBL3960874)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204556BDBM50204556(CHEMBL3941429)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204550BDBM50204550(CHEMBL3916935)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204545BDBM50204545(CHEMBL3898917)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
Tohoku Medical and Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50204555BDBM50204555(CHEMBL3983935)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2018
Entry Details Article
PubMed