Compile Data Set for Download or QSAR
Report error Found 5 of affinity data for UniProtKB/TrEMBL: P00439
TargetPhenylalanine-4-hydroxylase(Human)
University of Bergen

Curated by ChEMBL
LigandPNGBDBM50156156(2-Amino-7-(1,2-dihydroxy-propyl)-5,6,7,8-tetrahydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against human phenylalanine hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine-4-hydroxylase(Human)
University of Bergen

Curated by ChEMBL
LigandPNGBDBM729096(US12257253, Compound Hydrastinine)
Affinity DataKd:  2.99E+3nMAssay Description:ITC experiments were performed at 25° C. using a MicroCal PEAQ-ITC microcalorimeter (Malvern). PAH proteins were prepared in a HEPES buffer (HEPES 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2025
Entry Details

TargetPhenylalanine-4-hydroxylase(Human)
University of Bergen

Curated by ChEMBL
LigandPNGBDBM6644(Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...)
Affinity DataKd:  3.03E+3nMAssay Description:ITC experiments were performed at 25° C. using a MicroCal PEAQ-ITC microcalorimeter (Malvern). PAH proteins were prepared in a HEPES buffer (HEPES 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2025
Entry Details

TargetPhenylalanine-4-hydroxylase(Human)
University of Bergen

Curated by ChEMBL
LigandPNGBDBM50156156(2-Amino-7-(1,2-dihydroxy-propyl)-5,6,7,8-tetrahydr...)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity for human phenylalanine hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylalanine-4-hydroxylase(Human)
University of Bergen

Curated by ChEMBL
LigandPNGBDBM50373697(Sapropterin | TETRAHYDROBIOPTERIN | US12257253, Co...)
Affinity DataKd:  4.07E+4nMAssay Description:ITC experiments were performed at 25° C. using a MicroCal PEAQ-ITC microcalorimeter (Malvern). PAH proteins were prepared in a HEPES buffer (HEPES 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2025
Entry Details