Compile Data Set for Download or QSAR
Report error Found 97 for UniProtKB: P0A8V2
TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733296BDBM733296(US20250115594, Example 9)
Affinity DataIC50: 3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733340BDBM733340(US20250115594, Example 11)
Affinity DataIC50: 3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733337BDBM733337(US20250115594, Example 12)
Affinity DataIC50: 3nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733339BDBM733339(US20250115594, Example 8)
Affinity DataIC50: 4nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733336BDBM733336(US20250115594, Example 10)
Affinity DataIC50: 6nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733341BDBM733341(US20250115594, Example 13)
Affinity DataIC50: 20nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50391000BDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 20nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50391000BDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 30nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 733338BDBM733338(US20250115594, Example 14)
Affinity DataIC50: 50nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592137BDBM592137(US11572337, Compound 0MTK149)
Affinity DataIC50: 140nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592141BDBM592141(US11572337, Compound 0MTK158)
Affinity DataIC50: 220nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592173BDBM592173(US11572337, Compound 0MTK267)
Affinity DataIC50: 300nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592161BDBM592161(US11572337, Compound 0MTK237)
Affinity DataIC50: 310nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50155485BDBM50155485({(E)-5-[5-((2E,4E)-2,5-Dimethyl-nona-2,4-dienoyl)-...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592133BDBM592133(US11572337, Compound 0MTK127)
Affinity DataIC50: 370nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592145BDBM592145(US11572337, Compound 0MTK176)
Affinity DataIC50: 390nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592132BDBM592132(US11572337, Compound 0MTK107)
Affinity DataIC50: 400nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592142BDBM592142(US11572337, Compound 0MTK174)
Affinity DataIC50: 410nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592138BDBM592138(US11572337, Compound 0MTK154)
Affinity DataIC50: 420nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592144BDBM592144(US11572337, Compound 0MTK175)
Affinity DataIC50: 450nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592146BDBM592146(US11572337, Compound 0MTK178)
Affinity DataIC50: 610nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592164BDBM592164(US11572337, Compound 0MTK256)
Affinity DataIC50: 650nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592135BDBM592135(US11572337, Compound 0MTK146)
Affinity DataIC50: 690nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592175BDBM592175(US11572337, Compound 0MTK269)
Affinity DataIC50: 700nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592159BDBM592159(US11572337, Compound 0MTK232)
Affinity DataIC50: 720nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592162BDBM592162(US11572337, Compound 0MTK238)
Affinity DataIC50: 770nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592166BDBM592166(US11572337, Compound 0MTK260)
Affinity DataIC50: 780nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592139BDBM592139(US11572337, Compound 0MTK155)
Affinity DataIC50: 790nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592136BDBM592136(US11572337, Compound 0MTK148)
Affinity DataIC50: 800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592174BDBM592174(US11572337, Compound 0MTK268)
Affinity DataIC50: 800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592165BDBM592165(US11572337, Compound 0MTK257)
Affinity DataIC50: 800nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592170BDBM592170(US11572337, Compound 0MTK264)
Affinity DataIC50: 820nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592140BDBM592140(US11572337, Compound 0MTK156)
Affinity DataIC50: 820nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592147BDBM592147(US11572337, Compound 0MTK180)
Affinity DataIC50: 830nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50155484BDBM50155484(CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...)
Affinity DataIC50: 920nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592134BDBM592134(US11572337, Compound 0MTK128)
Affinity DataIC50: 970nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50155487BDBM50155487({(E)-5-[4-Hydroxy-5-((2E,4E)-2-methyl-nona-2,4-die...)
Affinity DataIC50: 1.04E+3nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592172BDBM592172(US11572337, Compound 0MTK266)
Affinity DataIC50: 1.20E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50155484BDBM50155484(CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...)
Affinity DataIC50: 1.26E+3nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592169BDBM592169(US11572337, Compound 0MTK263)
Affinity DataIC50: 1.30E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592171BDBM592171(US11572337, Compound 0MTK265)
Affinity DataIC50: 1.30E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592148BDBM592148(US11572337, Compound 0MTK181)
Affinity DataIC50: 1.40E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592168BDBM592168(US11572337, Compound 0MTK262)
Affinity DataIC50: 1.50E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592167BDBM592167(US11572337, Compound 0MTK261)
Affinity DataIC50: 1.50E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592149BDBM592149(US11572337, Compound 0MTK183)
Affinity DataIC50: 1.70E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 228835BDBM228835(MRL-436)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 592163BDBM592163(US11572337, Compound 0MTK240)
Affinity DataIC50: 2.10E+3nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 50155484BDBM50155484(CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against RNA polymerase of Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit alpha/beta/beta'/omega(Escherichia coli (strain K12))
The State University of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 50000054BDBM50000054(CHEMBL3228735)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Escherichia coli DNA-dependent RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Merck

LigandChemical structure of BindingDB Monomer ID 228835BDBM228835(MRL-436)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
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