Compile Data Set for Download or QSAR
Report error Found 879 of affinity data for UniProtKB/TrEMBL: P15090
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615297BDBM50615297(CHEMBL5272139)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212876BDBM50212876(2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid | CHE...)
Affinity DataKi:  2nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212873BDBM50212873(((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPH...)
Affinity DataKi: <2nMAssay Description:Inhibition of human FABP4 assessed as inhibition constant by fluorescent displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50192462BDBM50192462((S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxy...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to ap2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212885BDBM50212885([2'-(1-methyl-4,5-diphenyl-1H-imidazol-2-yl)-biphe...)
Affinity DataKi:  2.70nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212884BDBM50212884([2'-(1-ethyl-4,5-diphenyl-1H-imidazol-2-yl)-biphen...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid from aFABPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212877BDBM50212877([2'-(1-ethyl-4,5-diphenyl-1H-imidazol-2-yl)-biphen...)
Affinity DataKi:  3.40nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212886BDBM50212886([2'-(3-ethyl-4,5-diphenyl-furan-2-yl)-biphenyl-3-y...)
Affinity DataKi:  3.5nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212873BDBM50212873(((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPH...)
Affinity DataKd:  4nMAssay Description:Binding affinity to human FABP4 expressed in Escherichia coli assessed as degree of fluorescent shift by temperature-dependent fluorescence thermal s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346469BDBM50346469(2-(2'-(1-(4-chlorophenyl)-5-(thiophen-2-yl)-1H-pyr...)
Affinity DataKi:  5nMAssay Description:Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human a-FABP by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346465BDBM50346465(2-(2'-(1-(4-chlorophenyl)-5-(thiophen-2-yl)-1H-pyr...)
Affinity DataKi:  6nMAssay Description:Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human a-FABP by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029969BDBM50029969([2'-(4,5-Diphenyl-oxazol-2-yl)-biphenyl-3-yloxy]-a...)
Affinity DataKi:  6nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346468BDBM50346468(2-(2'-(1-(4-chlorophenyl)-5-(furan-2-yl)-1H-pyrazo...)
Affinity DataKi:  7nMAssay Description:Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human a-FABP by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197090BDBM50197090(CHEMBL3970105)
Affinity DataKi:  7nMAssay Description:Displacement of Bodipy-labeled fatty acid from recombinant human His6-tagged FABP4 expressed in Escherichia coli after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212873BDBM50212873(((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPH...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid from aFABPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212883BDBM50212883({2'-[1-(2-fluoro-ethyl)-4,5-diphenyl-1H-imidazol-2...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]2,3-bis[(2,4-dichlorobenzyl)oxy]benzoic acid from aFABPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312471BDBM312471(US9604977, Example 217 | 2-[5-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 9nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212879BDBM50212879([2'-(4,5-diphenyl-1H-imidazol-2-yl)-biphenyl-3-ylo...)
Affinity DataKi:  9.30nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312344BDBM312344(US9604977, Example 90 | 2-[3-(4-Trifluoromethyl-th...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50536996BDBM50536996(CHEMBL4581404)
Affinity DataKd:  10nMAssay Description:Binding affinity to recombinant FABP4 (unknown origin) expressed in Escherichia coli by sypro orange dye-based TdF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234674BDBM234674(US9353102, 3.3)
Affinity DataIC50: 10nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312490BDBM312490(US9604977, Example 236 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312313BDBM312313(US9604977, Example 61 | 2-[3-(3-Trifluoromethyl-[1...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312340BDBM312340(US9604977, Example 86 | 2-[3-(4-Trifluoromethyl-th...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312389BDBM312389(US9604977, Example 135 | 2-[3-(3-Trifluoromethyl-[...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312453BDBM312453(US9604977, Example 199 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234681BDBM234681(US9353102, 4.5)
Affinity DataIC50: 10nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312401BDBM312401(US9604977, Example 147 | 2-[6,6-Difluoro-3-(3-trif...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615295BDBM50615295(CHEMBL5278127)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FABP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615296BDBM50615296(CHEMBL5281007)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FABP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312314BDBM312314(US9604977, Example 62 | 3-[3-(3-Trifluoromethyl-[1...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312380BDBM312380(US9604977, Example 126 | 2-[3-(3-Trifluoromethyl-[...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50525617BDBM50525617(CHEMBL4560388)
Affinity DataKd:  10nMAssay Description:Binding affinity to human FABP4 expressed in Escherichia coli assessed as degree of fluorescent shift by temperature-dependent fluorescence thermal s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312350BDBM312350(US9604977, Example 96 | 2-[3-(4-Cyclopropyl-thiazo...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312382BDBM312382(US9604977, Example 128 | 3-[3-(3-Trifluoromethyl-[...)
Affinity DataIC50: 10nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234684BDBM234684(US9353102, 6.1)
Affinity DataIC50: 10nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234682BDBM234682(US9353102, 5)
Affinity DataIC50: 10nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312493BDBM312493(US9604977, Example 239 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 11nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234701BDBM234701(US9353102, 4.7)
Affinity DataIC50: 11nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197093BDBM50197093(CHEMBL3959018)
Affinity DataKi:  11nMAssay Description:Displacement of Bodipy-labeled fatty acid from recombinant human His6-tagged FABP4 expressed in Escherichia coli after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312465BDBM312465(US9604977, Example 211 | 3-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 12nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212887BDBM50212887([2'-(4,5-diphenyl-1H-pyrrol-2-yl)-biphenyl-3-yloxy...)
Affinity DataKi:  12nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197092BDBM50197092(CHEMBL3947458)
Affinity DataKi:  12nMAssay Description:Inhibition of FABP4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197092BDBM50197092(CHEMBL3947458)
Affinity DataKi:  12nMAssay Description:Displacement of Bodipy-labeled fatty acid from recombinant human His6-tagged FABP4 expressed in Escherichia coli after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312510BDBM312510(US9604977, Example 256 | (R)-1-[[3-[3-(trifluorome...)
Affinity DataIC50: 12nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312472BDBM312472(US9604977, Example 218 | 2-[3-(3-Cyclopropyl-[1,2,...)
Affinity DataIC50: 13nMAssay Description:Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234709BDBM234709(US9353102, 4.15)
Affinity DataIC50: 13nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197087BDBM50197087(CHEMBL3950316)
Affinity DataKi:  13nMAssay Description:Displacement of Bodipy-labeled fatty acid from recombinant human His6-tagged FABP4 expressed in Escherichia coli after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346467BDBM50346467(2-(2'-(1-(4-chlorophenyl)-5-phenyl-1H-pyrazol-3-yl...)
Affinity DataKi:  13nMAssay Description:Displacement of fluorescent 1-anilinonapthalene 8-sulfonic acid from human a-FABP by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Universita degli Studi di Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234707BDBM234707(US9353102, 4.13)
Affinity DataIC50: 13nMpH: 7.5Assay Description:Stock DMSO solutions (1.8 mM) of compounds were serially diluted 3-fold for ten concentrations with 100% DMSO (50 μM to 0.003 μM final comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

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