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Report error Found 32 of affinity data for UniProtKB/TrEMBL: P20035
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 92358BDBM92358(HGXPRT Inhibitor, 3)
Affinity DataKi:  0.650nM ΔG°:  -54.5kJ/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2012
Entry Details Article
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 50644379BDBM50644379(CHEMBL5573402)
Affinity DataKi:  10nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 92357BDBM92357(HGXPRT Inhibitor, 2)
Affinity DataKi:  10.6nM ΔG°:  -47.3kJ/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2012
Entry Details Article
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 50644378BDBM50644378(CHEMBL5591537)
Affinity DataKi:  60nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194493BDBM194493(US9200020, Table 3 compound 2 | BDBM50392259)
Affinity DataKi:  100nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60887BDBM60887(US9200020, Table 3, Compound 2B | BDBM50392248)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194490BDBM194490(US9200020, Table 1, Compound 1)
Affinity DataKi:  100nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194500BDBM194500(BDBM50392266 | US9200020, Table 3 compound 9)
Affinity DataKi:  100nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194496BDBM194496(BDBM50392261 | US9200020, Table 3 compound 5)
Affinity DataKi:  200nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60890BDBM60890(BDBM50392251 | US9200020, Table 3 compound 5B)
Affinity DataKi:  200nM ΔG°:  -39.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194501BDBM194501(BDBM50392263 | US9200020, Table 3 compound 10)
Affinity DataKi:  200nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194499BDBM194499(BDBM50392265 | US9200020, Table 3 compound 8)
Affinity DataKi:  200nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60880BDBM60880(US9200020, Table 1, Compound 1B)
Affinity DataKi:  300nM ΔG°:  -38.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194502BDBM194502(US9200020, Table 3 compound 11 | BDBM50392267)
Affinity DataKi:  300nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60897BDBM60897(US9200020, Table 3 compound 11B | BDBM50392257)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60893BDBM60893(US9200020, Table 3 compound 8B)
Affinity DataKi:  400nM ΔG°:  -38.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 50644375BDBM50644375(CHEMBL5563998)
Affinity DataKi:  500nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60892BDBM60892(BDBM50392254 | US9200020, Table 3 compound 7B)
Affinity DataKi:  600nM ΔG°:  -36.9kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194498BDBM194498(BDBM50392264 | US9200020, Table 3 compound 7)
Affinity DataKi:  700nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194494BDBM194494(BDBM50392260 | US9200020, Table 3 compound 3)
Affinity DataKi:  1.30E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194492BDBM194492(US9200020, Table 3 compound 1 | BDBM50392258)
Affinity DataKi:  1.70E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60886BDBM60886(US9200020, Table 3, Compound 1B | BDBM50392247)
Affinity DataKi:  1.90E+3nM ΔG°:  -34.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 50644377BDBM50644377(CHEMBL5565343)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60896BDBM60896(BDBM50392253 | US9200020, Table 3 compound 10B)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194497BDBM194497(BDBM50392262 | US9200020, Table 3 compound 6)
Affinity DataKi:  4.00E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60891BDBM60891(BDBM50392252 | US9200020, Table 3 compound 6B)
Affinity DataKi:  6.00E+3nM ΔG°:  -31.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 50644376BDBM50644376(CHEMBL5569467)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum HGXPRT by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194491BDBM194491(US9200020, Table 1, Compound 2 | BDBM50392245)
Affinity DataKi:  1.60E+4nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60884BDBM60884(US9200020, Table 1, Compound 2B)
Affinity DataKi: >2.00E+5nM ΔG°: >-22.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60894BDBM60894(BDBM50392256 | US9200020, Table 3 compound 9B)
Affinity DataKi: >2.10E+5nM ΔG°: >-21.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 60888BDBM60888(US9200020, Table 3, Compound 3B | BDBM50392249)
Affinity DataKi: >2.20E+5nM ΔG°: >-21.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandChemical structure of BindingDB Monomer ID 194495BDBM194495(BDBM50392250 | US9200020, Table 3 compound 4)
Affinity DataKi: >2.50E+5nM ΔG°: >-21.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent