Compile Data Set for Download or QSAR
Report error Found 97 for UniProtKB: P40145
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144001BDBM50144001(3-{4-[1-(2',4'-Dichloro-biphenyl-4-ylcarbamoyl)-he...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144020BDBM50144020(3-{4-[1-(4-Benzofuran-2-yl-phenylcarbamoyl)-heptyl...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144015BDBM50144015(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-octyl]...)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144008BDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  29nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144002BDBM50144002(3-{4-[2-(4-tert-Butyl-phenyl)-2-(2',4'-dichloro-bi...)
Affinity DataKi:  33nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144008BDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  69nMAssay Description:In vitro inhibitory activity against glucagon induced monkey adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004822BDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  71nMAssay Description:Compound was tested for the adenylate cyclase stimulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50010261BDBM50010261(colforsinum | cid_47936 | colforsina | colforsine ...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50537925BDBM50537925(CHEMBL4644318)
Affinity DataEC50:  105nMAssay Description:Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144003BDBM50144003(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...)
Affinity DataKi:  110nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144016BDBM50144016(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi:  144nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144009BDBM50144009(3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...)
Affinity DataKi:  254nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144004BDBM50144004(3-{4-[2-(Biphenyl-4-ylcarbamoyl)-2-(4-tert-butyl-p...)
Affinity DataKi:  300nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144012BDBM50144012(4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-phenyl)-...)
Affinity DataKi:  317nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604212BDBM50604212(CHEMBL5190252)
Affinity DataIC50: 380nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604214BDBM50604214(CHEMBL5170189)
Affinity DataIC50: 570nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144006BDBM50144006(3-{4-[2-(4-tert-Butyl-phenyl)-2-(quinolin-3-ylcarb...)
Affinity DataKi:  610nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604215BDBM50604215(CHEMBL5195432)
Affinity DataIC50: 700nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604227BDBM50604227(CHEMBL5182403)
Affinity DataIC50: 710nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604199BDBM50604199(CHEMBL5178772)
Affinity DataIC50: 780nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144005BDBM50144005(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-hydroxymethyl-p...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604200BDBM50604200(CHEMBL5205425)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604222BDBM50604222(CHEMBL5187427)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604213BDBM50604213(CHEMBL2098167 | TCMDC-142373 | GSK1783663A)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604218BDBM50604218(CHEMBL5197311)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604206BDBM50604206(CHEMBL5197376)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521058BDBM50521058(CHEMBL4456548)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604198BDBM50604198(CHEMBL5186455)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604228BDBM50604228(CHEMBL5178349)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604193BDBM50604193(CHEMBL5187824)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604211BDBM50604211(CHEMBL5186344)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144014BDBM50144014(3-{4-[2-(4-tert-Butyl-phenyl)-3-(4-ethyl-piperazin...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521074BDBM50521074(CHEMBL4467742)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144010BDBM50144010(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144013BDBM50144013(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144011BDBM50144011(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-ethyl-phenylcar...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144007BDBM50144007(3-{4-[2-(4-tert-Butyl-phenyl)-2-(3-ethyl-phenylcar...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144018BDBM50144018(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-pyrazol-1-yl-ph...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144000BDBM50144000(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-piperidin-1-yl-...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144017BDBM50144017(3-{4-[2-(4-tert-Butyl-phenyl)-3-oxo-3-(4-p-tolyl-p...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144019BDBM50144019(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604202BDBM50604202(CHEMBL5199983)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521109BDBM50521109(CHEMBL4585588)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation preincubated for 30 mins followed by A2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604201BDBM50604201(CHEMBL5203054)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604210BDBM50604210(CHEMBL5174303)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604204BDBM50604204(CHEMBL5188949)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604197BDBM50604197(CHEMBL5180340)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604223BDBM50604223(CHEMBL5193541)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604226BDBM50604226(CHEMBL5172009)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Kunming Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604208BDBM50604208(CHEMBL5202029)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Displayed 1 to 50 (of 97 total ) | Next | Last >>
Jump to: