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Report error Found 61 for UniProtKB: P40313
TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441773BDBM441773(US10640533, Table 1.20 | US10640533, Identificatio...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441775BDBM441775(US10640533, Table 1.22 | US10640533, Identificatio...)
Affinity DataIC50: 0.970nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441773BDBM441773(US10640533, Table 1.20 | US10640533, Identificatio...)
Affinity DataIC50: 1.09nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441775BDBM441775(US10640533, Table 1.22 | US10640533, Identificatio...)
Affinity DataIC50: 1.34nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50031442BDBM50031442(Alpha-ketocarbonyl derivative | 1N-[4-amino(nitroi...)
Affinity DataIC50: 2nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441779BDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 3.58nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441789BDBM441789(US10640533, Table 1.36 | US10640533, Identificatio...)
Affinity DataIC50: 3.73nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441789BDBM441789(US10640533, Table 1.36 | US10640533, Identificatio...)
Affinity DataIC50: 4.26nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441784BDBM441784(US10640533, Table 1.31 | US10640533, Identificatio...)
Affinity DataIC50: 4.28nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441779BDBM441779(US10640533, Table 1.26 | US10640533, Identificatio...)
Affinity DataIC50: 4.65nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441776BDBM441776(US10640533, Table 1.23 | US10640533, Identificatio...)
Affinity DataIC50: 4.74nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441776BDBM441776(US10640533, Table 1.23 | US10640533, Identificatio...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50031440BDBM50031440(Alpha-ketocarbonyl derivative | 1N-[4-amino(nitroi...)
Affinity DataIC50: 6nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441788BDBM441788(US10640533, Table 1.35 | US10640533, Identificatio...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441780BDBM441780(US10640533, Table 1.27 | US10640533, Identificatio...)
Affinity DataIC50: 6.56nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441787BDBM441787(US10640533, Table 1.34 | US10640533, Identificatio...)
Affinity DataIC50: 6.81nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441784BDBM441784(US10640533, Table 1.31 | US10640533, Identificatio...)
Affinity DataIC50: 7.41nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50288611BDBM50288611(Alpha-ketocarbonyl boronic ester derivative | CHEM...)
Affinity DataIC50: 8nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441790BDBM441790(US10640533, Table 1.37 | US10640533, Identificatio...)
Affinity DataIC50: 9.75nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441786BDBM441786(US10640533, Table 1.33 | US10640533, Identificatio...)
Affinity DataIC50: 11.1nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441787BDBM441787(US10640533, Table 1.34 | US10640533, Identificatio...)
Affinity DataIC50: 12.2nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441781BDBM441781(US10640533, Table 1.28 | US10640533, Identificatio...)
Affinity DataIC50: 13.5nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441786BDBM441786(US10640533, Table 1.33 | US10640533, Identificatio...)
Affinity DataIC50: 14.2nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441790BDBM441790(US10640533, Table 1.37 | US10640533, Identificatio...)
Affinity DataIC50: 15.3nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441785BDBM441785(US10640533, Table 1.32 | US10640533, Identificatio...)
Affinity DataIC50: 16nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50288609BDBM50288609(Alpha-ketocarbonyl derivative | CHEMBL317337)
Affinity DataIC50: 22nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50288609BDBM50288609(Alpha-ketocarbonyl derivative | CHEMBL317337)
Affinity DataIC50: 22nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441780BDBM441780(US10640533, Table 1.27 | US10640533, Identificatio...)
Affinity DataIC50: 28.1nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441785BDBM441785(US10640533, Table 1.32 | US10640533, Identificatio...)
Affinity DataIC50: 31.7nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441774BDBM441774(US10640533, Table 1.21 | US10640533, Identificatio...)
Affinity DataIC50: 33.3nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441774BDBM441774(US10640533, Table 1.21 | US10640533, Identificatio...)
Affinity DataIC50: 33.6nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441788BDBM441788(US10640533, Table 1.35 | US10640533, Identificatio...)
Affinity DataIC50: 59.3nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441781BDBM441781(US10640533, Table 1.28 | US10640533, Identificatio...)
Affinity DataIC50: 60.4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441778BDBM441778(US10640533, Table 1.25 | US10640533, Identificatio...)
Affinity DataIC50: 62.4nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50484478BDBM50484478(CHEMBL1929019 | jm5b01461, Compound 47)
Affinity DataIC50: 65nMAssay Description:Inhibition of chymotrypsin-like protease R188I mutant using peptide substrate SO1 measured after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50484484BDBM50484484(CHEMBL1929023)
Affinity DataIC50: 98nMAssay Description:Inhibition of chymotrypsin-like protease R188I mutant using peptide substrate SO1 measured after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441783BDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 113nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441782BDBM441782(US10640533, Table 1.29 | US10640533, Identificatio...)
Affinity DataIC50: 121nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50398607BDBM50398607(ONX 0912 | OPROZOMIB | US10640533, Identification ...)
Affinity DataIC50: 124nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441782BDBM441782(US10640533, Table 1.29 | US10640533, Identificatio...)
Affinity DataIC50: 170nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441778BDBM441778(US10640533, Table 1.25 | US10640533, Identificatio...)
Affinity DataIC50: 248nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50398607BDBM50398607(ONX 0912 | OPROZOMIB | US10640533, Identification ...)
Affinity DataIC50: 256nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50484483BDBM50484483(CHEMBL1929020 | acs.jmedchem.1c00409_ST.132)
Affinity DataIC50: 270nMAssay Description:Inhibition of chymotrypsin-like protease R188I mutant using peptide substrate SO1 measured after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50484491BDBM50484491(CHEMBL1929022 | acs.jmedchem.1c00409_ST.144)
Affinity DataIC50: 340nMAssay Description:Inhibition of chymotrypsin-like protease R188I mutant using peptide substrate SO1 measured after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50484487BDBM50484487(CHEMBL1929018 | acs.jmedchem.1c00409_ST.150)
Affinity DataIC50: 390nMAssay Description:Inhibition of chymotrypsin-like protease R188I mutant using peptide substrate SO1 measured after 60 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441783BDBM441783(US10640533, Table 1.30 | US10640533, Identificatio...)
Affinity DataIC50: 392nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441777BDBM441777(US10640533, Table 1.24 | US10640533, Identificatio...)
Affinity DataIC50: 500nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 441777BDBM441777(US10640533, Table 1.24 | US10640533, Identificatio...)
Affinity DataIC50: 500nMAssay Description:Inhibition of the chymotrypsin-like (CT-L), peptidylglutamyl peptide hydrolyzing activity (PGPH), and trypsin-like (T-L) activities of the 20S protea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50288610BDBM50288610(Alpha-ketocarbonyl derivative | CHEMBL98937)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsin-like protease CTRL-1(Human)
Centrax International

US Patent
LigandChemical structure of BindingDB Monomer ID 50288610BDBM50288610(Alpha-ketocarbonyl derivative | CHEMBL98937)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

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