Compile Data Set for Download or QSAR
Report error Found 55 of affinity data for UniProtKB/TrEMBL: P51635
LigandChemical structure of BindingDB Monomer ID 50009832BDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity was measured against renal inner medulla aldehyde reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16312BDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330615BDBM50330615(4-Amino-N-(4-bromo-2-fluorobenzyl)-N-(3,5-difluoro...)
Affinity DataIC50: 323nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126777BDBM50126777(Cyano-[5-fluoro-1-(4-fluoro-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 490nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126780BDBM50126780(Cyano-[5-fluoro-1-(4-methyl-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 690nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16314BDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 1.21E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50049730BDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 16312BDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 1.74E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 2.32E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126791BDBM50126791(Cyano-[1-(4-methyl-benzyl)-2-oxo-2,3-dihydro-1H-in...)
Affinity DataIC50: 3.57E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126774BDBM50126774(Cyano-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)-a...)
Affinity DataIC50: 6.79E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330610BDBM50330610(N-(4-(N-(3,5-Difluoro-4-hydroxyphenyl)sulfamoyl)ph...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330616BDBM50330616(N-(3,5-Difluoro-4-hydroxyphenyl)-N-(phenylsulfonyl...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50251025BDBM50251025(4-Amino-N-(3,5-difluoro-4-hydroxyphenyl)benzenesul...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330613BDBM50330613(N-(4-Bromo-2-fluorobenzyl)-N-(3,5-difluoro-4-hydro...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330611BDBM50330611(N-(4-(N-(3,5-Difluoro-4-hydroxyphenyl)sulfamoyl)ph...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50009832BDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity was measured against whole kidney aldehyde reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330614BDBM50330614(N-(4-Bromo-2-fluorobenzyl)-N-(3,5-difluoro-4-hydro...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50251023BDBM50251023(N-(3,5-Difluoro-4-hydroxyphenyl)benzenesulfonamide...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50251030BDBM50251030(N-(3,5-Difluoro-4-hydroxyphenyl)-4-methoxybenzenes...)
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330612BDBM50330612(N-(3,5-Difluoro-4-hydroxyphenyl)-4-(3-ethylureido)...)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056532BDBM50056532([3-(3-Nitro-benzyl)-4,5-dioxo-2-thioxo-imidazolidi...)
Affinity DataIC50: 2.80E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50009832BDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with DL-glyceraldehyde as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50003616BDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of rat kidney aldehyde reductase at 0.1 mM after 20 mins by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50003616BDBM50003616(Valproinsaeure | dipropylacetic acid | Di-n-propyl...)
Affinity DataIC50: 5.61E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056525BDBM50056525([4-Methylene-3-(3-nitro-benzyl)-2,5-dioxo-imidazol...)
Affinity DataIC50: 5.80E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056540BDBM50056540([3-(5-Chloro-benzothiazol-2-ylmethyl)-2,4,5-trioxo...)
Affinity DataIC50: 5.80E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056531BDBM50056531([3-(4-Chloro-benzothiazol-2-ylmethyl)-2,4,5-trioxo...)
Affinity DataIC50: 7.20E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50054328BDBM50054328(4-(3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-but...)
Affinity DataIC50: 9.26E+4nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50049729BDBM50049729([3-(3-Nitro-benzyl)-2,4,5-trioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against rat kidney aldehyde reductase (ALR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056527BDBM50056527([3-(4-Chloro-3-nitro-benzyl)-2,4-dioxo-3,4-dihydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056529BDBM50056529([3-(3-Nitro-benzyl)-2,4-dioxo-imidazolidin-1-yl]-a...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056530BDBM50056530([3-(3-Nitro-benzyl)-2,6-dioxo-3,6-dihydro-2H-pyrim...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056534BDBM50056534([3-(4-Chloro-benzothiazol-2-ylmethyl)-2,4-dioxo-3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056539BDBM50056539([3-(4-Chloro-benzothiazol-2-ylmethyl)-2,4-dioxo-im...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056535BDBM50056535([3-(4-Chloro-3-nitro-benzyl)-2,4,5-trioxo-imidazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056528BDBM50056528(CHEMBL160151 | CHEMBL351564 | [4-Hydroxy-3-(3-nitr...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056528BDBM50056528(CHEMBL160151 | CHEMBL351564 | [4-Hydroxy-3-(3-nitr...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056541BDBM50056541([2-Methylene-3-(3-nitro-benzyl)-4,5-dioxo-imidazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056538BDBM50056538({3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DI...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056526BDBM50056526([3-(3-Nitro-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056533BDBM50056533([3-(4-Chloro-3-nitro-benzyl)-2,4-dioxo-imidazolidi...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056536BDBM50056536([3-(3-Nitro-benzyl)-2,5-dioxo-imidazolidin-1-yl]-a...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50056537BDBM50056537([3-(3-Nitro-benzyl)-2,4,6-trioxo-tetrahydro-pyrimi...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50330608BDBM50330608(N-(3,5-Difluoro-4-hydroxyphenyl)-4-(trifluoromethy...)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50054324BDBM50054324((3-Oxo-3,5-dihydro-indeno[1,2-c]pyridazin-2-yl)-ac...)
Affinity DataIC50: 1.07E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50251024BDBM50251024(N-(3,5-Difluoro-4-hydroxyphenyl)-4-nitrobenzenesul...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50054316BDBM50054316(2-Carboxymethyl-3-oxo-3,5-dihydro-2H-indeno[1,2-c]...)
Affinity DataIC50: 1.36E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50054320BDBM50054320((3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-aceti...)
Affinity DataIC50: 1.56E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50054329BDBM50054329(2-Carboxymethyl-3-oxo-2,3,5,6-tetrahydro-benzo[h]c...)
Affinity DataIC50: 1.61E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
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