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TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 746820BDBM746820(US20250177582, Compound 28)
Affinity DataIC50: 0.00500nMAssay Description:Inhibition assay of FAP. The compounds were precisely weighed (range between 20-1000 pg) on a micro-scale (HuberLab, Sartorius QUINTIX35-1S) and diss...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 746808BDBM746808(US20250177582, Compound 9)
Affinity DataIC50: 0.115nMAssay Description:Inhibition assay of FAP. The compounds were precisely weighed (range between 20-1000 pg) on a micro-scale (HuberLab, Sartorius QUINTIX35-1S) and diss...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700141BDBM700141(US20240335569, Compound 3BP-3774)
Affinity DataIC50: 0.630nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700134BDBM700134(US20240335569, Compound 3BP-3621)
Affinity DataIC50: 0.630nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700702BDBM700702(US20240335569, Compound 3BP-3663)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700129BDBM700129(US20240335569, Compound 3BP-3469)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700119BDBM700119(US20240335569, Compound 3BP-3233)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700135BDBM700135(US20240335569, Compound 3BP-3622)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700146BDBM700146(US20240335569, Compound 3BP-3951)
Affinity DataIC50: 0.790nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700128BDBM700128(US20240335569, Compound 3BP-3468)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700127BDBM700127(US20240335569, Compound 3BP-3467)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700109BDBM700109(US20240335569, Compound 3BP-3126)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700143BDBM700143(US20240335569, Compound 3BP-3828)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700142BDBM700142(US20240335569, Compound 3BP-3785)
Affinity DataIC50: 1nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700151BDBM700151(US20240335569, Compound 3BP-4663)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700149BDBM700149(US20240335569, Compound 3BP-3954)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700148BDBM700148(US20240335569, Compound 3BP-3953)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700136BDBM700136(US20240335569, Compound 3BP-3631)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700144BDBM700144(US20240335569, Compound 3BP-3829)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700110BDBM700110(US20240335569, Compound 3BP-3127)
Affinity DataIC50: 1.26nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700139BDBM700139(US20240335569, Compound 3BP-3772)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700108BDBM700108(US20240335569, Compound 3BP-2929 | US20240382629, ...)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700704BDBM700704(US20240335569, Compound 3BP-4026)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700147BDBM700147(US20240335569, Compound 3BP-3952)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700154BDBM700154(US20240335569, Compound 3BP-4694)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700133BDBM700133(US20240335569, Compound 3BP-3611)
Affinity DataIC50: 1.58nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700703BDBM700703(US20240335569, Compound 3BP-4025)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700145BDBM700145(US20240335569, Compound 3BP-3830)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700115BDBM700115(US20240335569, Compound 3BP-3205)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700132BDBM700132(US20240335569, Compound 3BP-3582)
Affinity DataIC50: 2nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700706BDBM700706(US20240335569, Compound 3BP-4200)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009366BDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700152BDBM700152(US20240335569, Compound 3BP-4664)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700131BDBM700131(US20240335569, Compound 3BP-3581)
Affinity DataIC50: 2.51nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50434188BDBM50434188(CHEMBL2385281 | US9346814, Cmpd No 2 Example 3 | U...)
Affinity DataKi:  3nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700150BDBM700150(US20240335569, Compound 3BP-4201)
Affinity DataIC50: 3.16nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700156BDBM700156(US20240335569, Compound 3BP-4809)
Affinity DataIC50: 3.16nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700155BDBM700155(US20240335569, Compound 3BP-4808)
Affinity DataIC50: 3.16nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009366BDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009366BDBM50009366(CHEMBL3233842 | US9346814, Cmpd No 1, Example 1 | ...)
Affinity DataIC50: 3.20nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009364BDBM50009364(CHEMBL3233840)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009370BDBM50009370(CHEMBL3233847)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700137BDBM700137(US20240335569, Compound 3BP-3632)
Affinity DataIC50: 3.98nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50434169BDBM50434169(CHEMBL2385300 | US9346814, Cmpd No 22 Example 26)
Affinity DataKi:  4.10nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009360BDBM50009360(CHEMBL3233835 | US9346814, Cmpd No 23 Example 27)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50009360BDBM50009360(CHEMBL3233835 | US9346814, Cmpd No 23 Example 27)
Affinity DataIC50: 4.30nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700126BDBM700126(US20240335569, Compound 3BP-3412)
Affinity DataIC50: 5.01nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50434163BDBM50434163(CHEMBL2385273 | US9346814, Cmpd No 12 Example 15)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 50434163BDBM50434163(CHEMBL2385273 | US9346814, Cmpd No 12 Example 15)
Affinity DataIC50: 6.20nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Mouse)
Philochem

US Patent
LigandChemical structure of BindingDB Monomer ID 700705BDBM700705(US20240335569, Compound 3BP-4197)
Affinity DataIC50: 6.31nMAssay Description:Recombinant mouse FAP (R&D systems, #8647-SE) was diluted in assay buffer (50 mM Tris, 1 M NaCl, 1 mg/mL BSA, pH 7.5) to a concentration of 3.6 nM. 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

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