Compile Data Set for Download or QSAR
Report error Found 13 of affinity data for UniProtKB/TrEMBL: Q15796
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614609BDBM50614609(CHEMBL5271361)
Affinity DataIC50: 30nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614609BDBM50614609(CHEMBL5271361)
Affinity DataIC50: 30nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  33nMAssay Description:Binding affinity to human SMAD2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621293BDBM50621293(CHEMBL5439266)
Affinity DataIC50: 68nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621289BDBM50621289(CHEMBL5410106)
Affinity DataIC50: 68nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614612BDBM50614612(CHEMBL5280678)
Affinity DataIC50: 90nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614612BDBM50614612(CHEMBL5280678)
Affinity DataIC50: 90nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621292BDBM50621292(CHEMBL5405214)
Affinity DataIC50: 100nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614611BDBM50614611(CHEMBL3400936)
Affinity DataIC50: 137nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621291BDBM50621291(CHEMBL5434170)
Affinity DataIC50: 140nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614611BDBM50614611(CHEMBL3400936)
Affinity DataIC50: 140nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621290BDBM50621290(CHEMBL5403707)
Affinity DataIC50: 240nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614610BDBM50614610(CHEMBL5267203)
Affinity DataIC50: 240nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed