Compile Data Set for Download or QSAR
Report error Found 226 of affinity data for UniProtKB/TrEMBL: Q6P6C2
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592094BDBM50592094(CHEMBL5203605)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592105BDBM50592105(CHEMBL5172537)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624931BDBM624931(US20230322715, Compound TR-ALKBH5-29)
Affinity DataIC50: 110nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060768BDBM50060768(9,10-anthracenedicarboxaldehyde Bis[(4,5-dihydro-1...)
Affinity DataIC50: 140nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using 5'-ATTGTCA(m6A)CAGCAGA-FAM-3' as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624926BDBM624926(US20230322715, Compound TR-ALKBH5-04)
Affinity DataIC50: 240nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624942BDBM624942(US20230322715, Compound TR-ALKBH5-42)
Affinity DataIC50: 250nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592118BDBM50592118(CHEMBL5205465)
Affinity DataIC50: 396nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624937BDBM624937(US20230322715, Compound TR-ALKBH5-36)
Affinity DataIC50: 400nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592104BDBM50592104(CHEMBL5175898)
Affinity DataIC50: 421nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624941BDBM624941(US20230322715, Compound TR-ALKBH5-41)
Affinity DataIC50: 450nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624928BDBM624928(US20230322715, Compound TR-ALKBH5-08)
Affinity DataIC50: 500nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592117BDBM50592117(CHEMBL5186162)
Affinity DataIC50: 559nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592096BDBM50592096(CHEMBL5208142)
Affinity DataIC50: 591nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15339BDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 710nMAssay Description:Inhibition of ALKBH5 (66 to 292 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using 5'-ATTGTCA(m6A)CAGCAGA-FAM-3' as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592100BDBM50592100(CHEMBL5180828)
Affinity DataIC50: 727nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557836BDBM50557836(CHEMBL4752151)
Affinity DataIC50: 840nMAssay Description:Inhibition of N-terminal ALKBH5 (unknown origin) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557836BDBM50557836(CHEMBL4752151)
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant ALKBH5 (unknown origin) mediated demethylase activity using methylated N6-adenine RNA probe with CUUGUCAm6ACAGCAGA sequence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557836BDBM50557836(CHEMBL4752151)
Affinity DataIC50: 840nMAssay Description:Inhibition of ALKBH5 demethylase activity (unknown origin) assessed as increase in methylated 6A-RNA level incubated for 2 hrs by colorimetric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599016BDBM50599016(CHEMBL5198269 | US20230322715, Compound TR-FTO-16)
Affinity DataIC50: 870nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592116BDBM50592116(CHEMBL5202184)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624919BDBM624919(US20230322715, Compound ALK-25)
Affinity DataIC50: 900nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624905BDBM624905(US20230322715, Compound ALK-04)
Affinity DataIC50: 900nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624874BDBM624874(US20230322715, Compound TR-FTO-39)
Affinity DataIC50: 920nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599024BDBM50599024(CHEMBL5188113)
Affinity DataIC50: 920nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624932BDBM624932(US20230322715, Compound TR-ALKBH5-30)
Affinity DataIC50: 1.00E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50416557BDBM50416557(CHEMBL5282066)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624920BDBM624920(US20230322715, Compound ALK-30)
Affinity DataIC50: 1.40E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647354BDBM50647354(CHEMBL5597347)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624929BDBM624929(US20230322715, Compound TR-ALKBH5-25)
Affinity DataIC50: 1.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357221BDBM50357221(CHEMBL442218 | US20230322715, Compound ALK-10)
Affinity DataIC50: 1.70E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557837BDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of N-terminal ALKBH5 (unknown origin) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557837BDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of recombinant ALKBH5 (unknown origin) mediated demethylase activity using methylated N6-adenine RNA probe with CUUGUCAm6ACAGCAGA sequence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557837BDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of ALKBH5 demethylase activity (unknown origin) assessed as increase in methylated 6A-RNA level incubated for 2 hrs by colorimetric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human full length N-terminal His6-tagged ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592071BDBM50592071(CHEMBL5169684)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of N-terminal truncated human ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624938BDBM624938(US20230322715, Compound TR-ALKBH5-38)
Affinity DataIC50: 1.90E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624927BDBM624927(US20230322715, Compound TR-ALKBH5-05)
Affinity DataIC50: 1.90E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50485565BDBM50485565(CHEMBL465179)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624930BDBM624930(US20230322715, Compound TR-ALKBH5-27)
Affinity DataIC50: 2.00E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624934BDBM624934(US20230322715, Compound TR-ALKBH5-32)
Affinity DataIC50: 2.20E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599013BDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)
Affinity DataIC50: 2.30E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599013BDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624940BDBM624940(US20230322715, Compound TR-ALKBH5-40)
Affinity DataIC50: 2.30E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599017BDBM50599017(CHEMBL5195274 | US20230322715, Compound TR-FTO-17)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599017BDBM50599017(CHEMBL5195274 | US20230322715, Compound TR-FTO-17)
Affinity DataIC50: 2.50E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599033BDBM50599033(CHEMBL5208226)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624935BDBM624935(US20230322715, Compound TR-ALKBH5-33)
Affinity DataIC50: 2.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624880BDBM624880(US20230322715, Compound TR-FTO-48)
Affinity DataIC50: 2.60E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592109BDBM50592109(CHEMBL5195733)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of human recombinant ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) cells using FAM-labeled ssRNA (5'-CUCGAUACG(m^6A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
Nankai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 624918BDBM624918(US20230322715, Compound ALK-23)
Affinity DataIC50: 2.80E+3nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

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