Compile Data Set for Download or QSAR
Report error Found 32 of affinity data for UniProtKB/TrEMBL: Q9Y5A9
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624885BDBM624885(US20230322715, Compound TR-YTH-05)
Affinity DataKi:  0.0700nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624887BDBM624887(US20230322715, Compound TR-YTH-07)
Affinity DataKi:  0.0770nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624883BDBM624883(US20230322715, Compound TR-YTH-03)
Affinity DataKi:  0.0850nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624898BDBM624898(US20230322715, Compound TR-YTH-18)
Affinity DataKi:  0.0950nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624884BDBM624884(US20230322715, Compound TR-YTH-04)
Affinity DataKi:  0.100nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624881BDBM624881(US20230322715, Compound TR-YTH-01)
Affinity DataKi:  0.102nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624890BDBM624890(US20230322715, Compound TR-YTH-10)
Affinity DataKi:  0.106nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624900BDBM624900(US20230322715, Compound TR-YTH-19)
Affinity DataKi:  0.107nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624894BDBM624894(US20230322715, Compound TR-YTH-14)
Affinity DataKi:  0.128nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624895BDBM624895(US20230322715, Compound TR-YTH-15)
Affinity DataKi:  0.145nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624893BDBM624893(US20230322715, Compound TR-YTH-13)
Affinity DataKi:  0.150nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624889BDBM624889(US20230322715, Compound TR-YTH-09)
Affinity DataKi:  0.172nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624896BDBM624896(US20230322715, Compound TR-YTH-16)
Affinity DataKi:  0.179nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624882BDBM624882(US20230322715, Compound TR-YTH-02)
Affinity DataKi:  0.182nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624901BDBM624901(US20230322715, Compound TR-YTH-20)
Affinity DataKi:  0.266nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624897BDBM624897(US20230322715, Compound TR-YTH-17)
Affinity DataKi:  0.333nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624886BDBM624886(US20230322715, Compound TR-YTH-06)
Affinity DataKi:  0.395nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624892BDBM624892(US20230322715, Compound TR-YTH-12)
Affinity DataKi:  0.850nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 624891BDBM624891(US20230322715, Compound TR-YTH-11)
Affinity DataKi:  5.59nMAssay Description:The in vitro inhibition assay method was adapted from Svenson and Jaffrey, 2016. All reactions were performed in a 96-well plate with 200 μL ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  68nMAssay Description:Binding affinity to human YTHDF2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50636844BDBM50636844(CHEMBL5542345)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of GST-tagged YTHDF2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601384BDBM50601384(CHEMBL5205586)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of GST-tagged YTHDF2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601384BDBM50601384(CHEMBL5205586)
Affinity DataIC50: 1.61E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601386BDBM50601386(CHEMBL5201513)
Affinity DataIC50: 1.61E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601383BDBM50601383(CHEMBL5177286)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601385BDBM50601385(CHEMBL5192478)
Affinity DataIC50: 1.74E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601385BDBM50601385(CHEMBL5192478)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of GST-tagged YTHDF2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601383BDBM50601383(CHEMBL5177286)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of GST-tagged YTHDF2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601383BDBM50601383(CHEMBL5177286)
Affinity DataIC50: 4.10E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601385BDBM50601385(CHEMBL5192478)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601384BDBM50601384(CHEMBL5205586)
Affinity DataIC50: 4.91E+5nMAssay Description:Inhibition of YTHDF2 YTH domain (unknown origin) (383 to 579 residues) expressed as Escherichia coli BL21 (DE3) Rosetta cells by HTFR based binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetYTH domain-containing family protein 2(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 50601386BDBM50601386(CHEMBL5201513)
Affinity DataIC50: 4.91E+5nMAssay Description:Binding affinity to GST-tagged YTHDF2 m6A-reader domain (unknown origin) using RRACH-containing methylated oligoRNA incubated for 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)