Compile Data Set for Download or QSAR
Report error Found 47 of affinity data for UniProtKB/TrEMBL: Q9Z0J4
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330882BDBM50330882(CHEMBL1277951 | CHEMBL594682 | N1-((3R,4R)-4-((6-a...)
Affinity DataKi:  5nMAssay Description:Inhibition of recombinant mouse nNOS overexpressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138191BDBM50138191(ONO-1714 | (1S,5S,6R,7R)-7-Chloro-5-methyl-2-aza-b...)
Affinity DataIC50: 15nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255365BDBM50255365(CHEMBL1277870 | (+/-)-cis-N1-((3S,4S)-4-((6-amino-...)
Affinity DataKi:  52nMAssay Description:Inhibition of recombinant mouse nNOS overexpressed in Escherichia coli assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138186BDBM50138186(5-Bromomethyl-oxazolidin-(2Z)-ylideneamine | CHEMB...)
Affinity DataIC50: 400nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225106BDBM50225106(NG-nitroarginine | 2-Amino-5-(N'-nitro-guanidino)-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138190BDBM50138190((4S,5S)-5-Methyl-4-propyl-oxazolidin-(2Z)-ylidenea...)
Affinity DataIC50: 570nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138192BDBM50138192((4S,5R)-4-Ethyl-5-methyl-oxazolidin-(2Z)-ylideneam...)
Affinity DataIC50: 680nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138200BDBM50138200((4S,5S)-5-Methyl-4-pentyl-oxazolidin-(2Z)-ylidenea...)
Affinity DataIC50: 790nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138185BDBM50138185((4S,5R)-5-Ethyl-4-methyl-oxazolidin-(2Z)-ylideneam...)
Affinity DataIC50: 850nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138189BDBM50138189((4S,5R)-5-Methyl-4-propyl-oxazolidin-(2Z)-ylidenea...)
Affinity DataIC50: 920nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138198BDBM50138198((4S,5R)-4,5-Diethyl-oxazolidin-(2Z)-ylideneamine |...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138201BDBM50138201(5-Methyl-oxazolidin-(2Z)-ylideneamine | CHEMBL1074...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138184BDBM50138184((4S,5R)-4,5-Dimethyl-oxazolidin-(2Z)-ylideneamine ...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138194BDBM50138194((4S,5S)-5-Ethyl-4-methyl-oxazolidin-(2Z)-ylideneam...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138193BDBM50138193(5-Ethyl-oxazolidin-(2Z)-ylideneamine | CHEMBL10835...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138187BDBM50138187((4S,5S)-4-Ethyl-5-methyl-oxazolidin-(2Z)-ylideneam...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138195BDBM50138195((4S,5S)-4,5-Diethyl-oxazolidin-(2Z)-ylideneamine |...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138188BDBM50138188(4-Ethyl-oxazolidin-(2Z)-ylideneamine | CHEMBL10878...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072297BDBM50072297(5-Acetimidoylamino-2-(S)-amino-pentanoic acid | CH...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344422BDBM344422(US9783500, Compound 17)
Affinity DataKi:  3.34E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344421BDBM344421(US9783500, Compound 16)
Affinity DataKi:  3.42E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138196BDBM50138196((4S,5R)-5-Methyl-4-pentyl-oxazolidin-(2Z)-ylidenea...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230993BDBM50230993(CHEMBL256147 | 2-Amino-5-(N'-methyl-guanidino)-pen...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344419BDBM344419(US9783500, Compound 14)
Affinity DataKi:  5.44E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344408BDBM344408(US9783500, Compound 4 | US9783500, Compound 10)
Affinity DataKi:  5.75E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344416BDBM344416(US9783500, Compound 11)
Affinity DataKi:  6.70E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344425BDBM344425(US9783500, Compound (R)-19)
Affinity DataKi:  7.35E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344417BDBM344417(US9783500, Compound 12)
Affinity DataKi:  7.44E+3nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138202BDBM50138202(4-Methyl-oxazolidin-(2Z)-ylideneamine | CHEMBL1058...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344424BDBM344424(US9783500, Compound rac-19)
Affinity DataKi:  1.08E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344413BDBM344413(US9783500, Compound 8)
Affinity DataKi:  1.25E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344418BDBM344418(US9783500, Compound 13)
Affinity DataKi:  1.30E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344410BDBM344410(US9783500, Compound 6 | US9783500, Compound 18)
Affinity DataKi:  1.52E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344409BDBM344409(US9783500, Compound 5)
Affinity DataKi:  1.68E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344420BDBM344420(US9783500, Compound 15)
Affinity DataKi:  1.99E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344426BDBM344426(US9783500, Compound (S)-19)
Affinity DataKi:  2.56E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344410BDBM344410(US9783500, Compound 6 | US9783500, Compound 18)
Affinity DataKi:  2.57E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344408BDBM344408(US9783500, Compound 4 | US9783500, Compound 10)
Affinity DataKi:  2.77E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099401BDBM50099401(1-(2-Trifluoromethyl-phenyl)-1H-imidazole | CHEMBL...)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of mouse nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330882BDBM50330882(CHEMBL1277951 | CHEMBL594682 | N1-((3R,4R)-4-((6-a...)
Affinity DataKi:  2.84E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344412BDBM344412(US9783500, Compound 7)
Affinity DataKi:  3.27E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344407BDBM344407(US9783500, Compound 3)
Affinity DataKi:  3.32E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50078037BDBM50078037(Oxazolidin-(2Z)-ylideneamine | CHEMBL69446)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 344414BDBM344414(US9783500, Compound 9)
Affinity DataKi:  4.05E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330882BDBM50330882(CHEMBL1277951 | CHEMBL594682 | N1-((3R,4R)-4-((6-a...)
Affinity DataKi:  4.40E+4nMAssay Description:Rat and human nNOS, murine macrophage iNOS, and human eNOS were recombinant enzymes (expressed in E. coli and purified as reported previously in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138197BDBM50138197((4S,5R)-4,5-Dipropyl-oxazolidin-(2Z)-ylideneamine ...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Mouse)
Flinders University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50138199BDBM50138199((4S,5S)-4,5-Dipropyl-oxazolidin-(2Z)-ylideneamine ...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed