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[1,2,4]Triazolo[1,5-a]pyrimidine derivatives: Structure-activity relationship study leading to highly selective ENPP1 inhibitors.
Bioorg Med Chem Lett 110: 0-0 (0)
Nagoya City University
Revisiting the antiangiogenic mechanisms of fluorinated thalidomide derivatives.
Bioorg Med Chem Lett 110: 0-0 (0)
University of Bonn
Synthesis and activity of benzimidazole N-Acylhydrazones against Trypanosoma cruzi, Leishmania amazonensis and Leishmania infantum.
Bioorg Med Chem Lett 110: 0-0 (0)
Instituto de Tecnologia em Farmacos
Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment.
Bioorg Med Chem Lett 110: 0-0 (0)
Kyorin Pharmaceutical Co. Ltd.
Structure-activity relationship of dual inhibitors containing maleimide and imidazole motifs against glutaminyl cyclase and glycogen synthase kinase-3β.
Bioorg Med Chem Lett 110: 0-0 (0)
Shenzhen University Medical School
Machine learning-based QSAR and LB-PaCS-MD guided design of SARS-CoV-2 main protease inhibitors.
Bioorg Med Chem Lett 110: 0-0 (0)
Chulalongkorn University
Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety.
Bioorg Med Chem Lett 110: 0-0 (0)
Japan Tobacco
Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity.
Bioorg Med Chem Lett 110: 0-0 (0)
University of Dundee
Synthesis, biosimulation and pharmacological evaluation of benzimidazole derivatives with antihypertensive multitarget effect.
Bioorg Med Chem Lett 110: 0-0 (0)
Universidad Autonoma del Estado de Morelos
N-methylmorpholine incorporation into the structure of biphenyl leads to the bioactive inhibitor of PD-1/PD-L1 interaction.
Bioorg Med Chem Lett 110: 0-0 (0)
Jagiellonian University
Plakevulin A induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells.
Bioorg Med Chem Lett 110: 0-0 (0)
Tokyo University of Science
2-(Piperidin-3-yl)phthalimides reduce classical markers of cellular inflammation in LPS-challenged RAW 264.7 cells and also demonstrate potentially relevant sigma and serotonin receptor affinity in membrane preparations.
Bioorg Med Chem Lett 110: 0-0 (0)
National Institute on Aging