The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

17 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
35
Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease.EBI
Albany Molecular Research
23
Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds.EBI
Albany Molecular Research
1
Synthesis of enantiomerically pure (+)- and (-)-18-methoxycoronaridine hydrochloride and their preliminary assessment as anti-addictive agents.EBI
Albany Molecular Research
27
Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereofBDB
Albany Molecular Research
36
Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotoninBDB
Albany Molecular Research
10
Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereofBDB
Albany Molecular Research
201
Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-HT6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophreniaBDB
Albany Molecular Research
26
5-HT3 receptor modulators, methods of making, and use thereofBDB
Albany Molecular Research
55
2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotoninBDB
Albany Molecular Research
26
Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereofBDB
Albany Molecular Research
26
Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereofBDB
Albany Molecular Research
111
Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereofBDB
Albany Molecular Research
40
Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereofBDB
Albany Molecular Research
52
Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereofBDB
Albany Molecular Research
22
SGLT-2 inhibitors, methods of making them, and uses thereofBDB
Albany Molecular Research
152
Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereofBDB
Albany Molecular Research
34
5-HT3 receptor modulators, methods of making, and use thereofBDB
Albany Molecular Research