BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

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10 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
9
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models.EBI
Arvinas
19
Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1.EBI
Arvinas
46
Cereblon ligands and bifunctional compounds comprising the sameBDB
Arvinas
46
CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAMEBDB
Arvinas
378
Modulators of BCL6 proteolysis and associated methods of useBDB
Arvinas
139
Compounds and methods for the enhanced degradation of targeted proteinsBDB
Arvinas
55
Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptidesBDB
Arvinas
108
EGFR proteolysis targeting chimeric molecules and associated methods of useBDB
Arvinas
11
Tank-binding kinase-1 PROTACs and associated methods of useBDB
Arvinas
140
Compounds and methods for the enhanced degradation of targeted proteinsBDB
Arvinas