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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 743K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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19 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Structure-Based Inhibitor Design for Evaluation of a CYP3A4 Pharmacophore Model.EBI
University of California Irvine
Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization.EBI
University of California Irvine
Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of a7 nicotinic acetylcholine receptors.EBI
University of California Irvine
Modified norcantharidins; synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity.EBI
University of California Irvine
The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.EBI
University of California Irvine
Enaminone amides as novel orally active GABAA receptor modulators.EBI
University of California Irvine
Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors.EBI
University of California Irvine
Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A.EBI
University of California Irvine
Compounds and compositions as inhibitors of MEKBDB
Novartis
 
ERK2 in CSAR_FULL_RELEASE_3JULY2012BDB
Csar
Endocrinological properties of two novel nonsteroidal progesterone receptor modulators, CP8816 and CP8863.BDB
Meiji Seika Kaisha
Dual aromatase-steroid sulfatase inhibitors.BDB
University of Bath
Indole naphthyridinones as inhibitors of bacterial enoyl-ACP reductases FabI and FabK.BDB
Glaxosmithkline
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.BDB
Boehringer Ingelheim Pharmaceuticals