22 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
A novel series of histone deacetylase inhibitors incorporating hetero aromatic ring systems as connection units.
Abbott Laboratories
Indole amide hydroxamic acids as potent inhibitors of histone deacetylases.
Abbott Laboratories
Design, synthesis and in vitro evaluation of amidoximes as histone deacetylase inhibitors for cancer therapy.
Qilu Normal University
Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors.
Shandong University
Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.
Fudan University
Discovery of 2,5-diphenyl-1,3,4-thiadiazole derivatives as HDAC inhibitors with DNA binding affinity.
Qilu University of Technology (Shandong Academy of Sciences)
HDAC as onco target: Reviewing the synthetic approaches with SAR study of their inhibitors.
Indian Csir-Central Drug Research Institute
Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma.
Shandong University
14- and 15-membered lactone macrolides and their analogues and hybrids: structure, molecular mechanism of action and biological activity.
Adam Mickiewicz University
Design, synthesis and biological evaluation of saccharin-based N-hydroxybenzamides as histone deacetylases (HDACs) inhibitors.
Shandong University
Design, synthesis and preliminary bioactivity evaluations of substituted quinoline hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors.
Shandong University
Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity.
Shandong University
Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells.
Csir-Indian Institute of Chemical Technology
Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif.
Shandong University
Design, synthesis and preliminary bioactivity studies of 1,2-dihydrobenzo[d]isothiazol-3-one-1,1-dioxide hydroxamic acid derivatives as novel histone deacetylase inhibitors.
Shandong University
Design, synthesis and preliminary biological evaluation of N-hydroxy-4-(3-phenylpropanamido)benzamide (HPPB) derivatives as novel histone deacetylase inhibitors.
Shandong University
Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors.
Shandong University
Indole in the target-based design of anticancer agents: A versatile scaffold with diverse mechanisms.
Mazandaran University of Medical Sciences
Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors.
Shandong University
