BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.2M Compounds and 9.3K Targets. Of those, 1,352K data for 627K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads.EBI
Agios Pharmaceuticals
Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors.EBI
China Pharmaceutical University
Fragment-Based Design of a Potent MAT2a Inhibitor and EBI
Astrazeneca
Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous EBI
Agios Pharmaceuticals
Methionine Adenosyltransferase Inhibitors for the Treatment of Cancer.EBI
Usona Institute
Exploiting binding-site arginines in drug design: Recent examples.EBI
Prelude Therapeutics