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42 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor Agents.EBI
China Pharmaceutical University
Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy.EBI
Southern Medical University
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.EBI
Merck
Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor.EBI
Korea Research Institute of Chemical Technology
Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration.EBI
China Pharmaceutical University
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists.EBI
Shanghai Jiao Tong University
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.EBI
Czech Academy of Sciences
Small molecule approaches to treat autoimmune and inflammatory diseases (Part II): Nucleic acid sensing antagonists and inhibitors.EBI
Roche Innovation Center Shanghai
STING, a promising target for small molecular immune modulator: A review.EBI
China Pharmaceutical University
Discovery of Non-Nucleotide Small-Molecule STING Agonists EBI
Bristol Myers Squibb Research and Development
Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.EBI
Takeda Pharmaceuticals International
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP).EBI
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences
Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists.EBI
Chinese Academy of Sciences
The discovery of potent small molecule activators of human STING.EBI
Curadev Pharma
Design, Synthesis, and Biological Evaluation of Novel Cyclic Adenosine-Inosine Monophosphate (cAIMP) Analogs That Activate Stimulator of Interferon Genes (STING).EBI
Invivogen
Targeting Stimulator of Interferon Genes (STING) for the Potential Treatment of Cancer and Infectious Diseases.EBI
Usona Institute
Synthesis and biological evaluation of all possible inosine-mixed cyclic dinucleotides that activate different hSTING variants.EBI
Nankai University
Novel Compounds as STING Modulators for Treating Hepatitis B Virus Infections.EBI
Smith, Gambrell & Russell
Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes.EBI
Therachem Research Medilab
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.EBI
Merck
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.EBI
China Pharmaceutical University
Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.EBI
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences and Gilead Sciences Research Centre At Iocb
STING modulators: Predictive significance in drug discovery.EBI
Zhejiang Normal University
Design, Synthesis, and Biological Evaluation of Amidobenzimidazole Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists.EBI
Peking Union Medical College and Chinese Academy of Medical Sciences
A high quality, industrial data set for binding affinity prediction: performance comparison in different early drug discovery scenarios.BDB
F. Hoffmann-La Roche
Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding.BDB
Gsk