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24 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.EBI
Indiana University School of Medicine
Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B.EBI
Saint John'S University
Calix[4]arene methylenebisphosphonic acids as inhibitors of protein tyrosine phosphatase 1B.EBI
National Academy of Sciences of Ukraine
A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.EBI
Indiana University School of Medicine
Arylstibonic acids are potent and isoform-selective inhibitors of Cdc25a and Cdc25b phosphatases.EBI
Imperial College
Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.EBI
Indiana University School of Medicine
Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening.EBI
Purdue University
5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases.EBI
Universit£
Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.EBI
University of Waterloo
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.EBI
University of California
Recent advances in the discovery of competitive protein tyrosine phosphatase 1B inhibitors for the treatment of diabetes, obesity, and cancer.EBI
Incyte
Inhibition of Yersinia protein tyrosine phosphatase by phosphonate derivatives of calixarenes.EBI
National Academy of Sciences of Ukraine
Knowledge-based characterization of similarity relationships in the human protein-tyrosine phosphatase family for rational inhibitor design.EBI
University of Miami
Recent developments in fragment-based drug discovery.EBI
Astex Therapeutics
Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.EBI
Eli Lilly
Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.EBI
Procter & Gamble Pharmaceuticals
Inhibition of Low Molecular Weight Protein Tyrosine Phosphatase by an Induced-Fit Mechanism.EBI
Purdue University
Highly Potent and Selective EBI
Purdue University
PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.EBI
Wyeth-Ayerst Research