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10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an ImprovedEBI
Genentech
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.EBI
Pharmaron-Beijing
Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity.EBI
Takeda Pharmaceutical
SAGE-718: A First-in-Class EBI
Sage Therapeutics
Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.EBI
Parke-Davis Pharmaceutical Research
1EBI
Janssen Research & Development
Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action.EBI
University of Bristol
A New Class of Potent N-Methyl-D-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications.EBI
Academy of Sciences of The Czech Republic V.V.I.
Characterization of [3H]quinpirole binding to D2-like dopamine receptors in rat brain.BDB
Dupont Pharmaceuticals