25 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction.
Y.B. Chavan College of Pharmacy
Identification of novel aminopiperidine derivatives for antibacterial activity against Gram-positive bacteria.
Research Laboratories Ildong Pharmaceutical
Peptide deformylase inhibitors with retro-amide scaffold: synthesis and structure-activity relationships.
Seoul National University
Macrolactin N, a new peptide deformylase inhibitor produced by Bacillus subtilis.
Korea Research Institute of Bioscience and Biotechnology
Acylprolinamides: a new class of peptide deformylase inhibitors with in vivo antibacterial activity.
Glaxosmithkline
Flavimycins A and B, dimeric 1,3-dihydroisobenzofurans with peptide deformylase inhibitory activity from Aspergillus flavipes.
Korea Research Institute of Bioscience and Biotechnology
Discovery and refinement of a new structural class of potent peptide deformylase inhibitors.
Centre National De La Recherche Scientifique
Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
F. Hoffmann-La Roche
Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains.
British Biotech Pharmaceuticals
Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase.
Memorial Sloan-Kettering Cancer Center
Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.
Seoul National University
Peptide deformylase inhibitors of Mycobacterium tuberculosis: synthesis, structural investigations, and biological results.
Novartis Institute For Tropical Diseases
Macrolactins O-R, glycosylated 24-membered lactones from Bacillus sp. AH159-1.
Korea Research Institute of Bioscience and Biotechnology
Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size.
The Ohio State University
Identification of novel potent bicyclic peptide deformylase inhibitors.
Genomics Institute of The Novartis Research Foundation
Peptide deformylase inhibitors with activity against respiratory tract pathogens.
British Biotech Pharmaceuticals
Structure-based design of a macrocyclic inhibitor for peptide deformylase.
The Ohio State University
2-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)- and 2-(2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl)-N-hydroxy-acetamides as potent and selective peptide deformylase inhibitors.
F. Hoffmann-La Roche
Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition.
Pharmacia
Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections.
Glaxosmithkline