PMID

Data

Article Title

Organization

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

Cellzome

A one-pot synthesis and biological activity of ageladine A and analogues.

Macquarie University

A quantitative analysis of kinase inhibitor selectivity.

Ambit Biosciences

Comprehensive analysis of kinase inhibitor selectivity.

Ambit Biosciences

AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).

Ambit Biosciences

Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.

Astrazeneca

Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK).

University of North Carolina At Chapel Hill

Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.

Biocon Bristol Myers Squibb Research Center

SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK).

Johann Wolfgang Goethe University

Kinase Chemodiversity from the Arctic: The Breitfussins.

Uit - The Arctic University of Norway

Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88

Astrazeneca

Synthesis and biological evaluation of some new N(4)-substituted isatin-3-thiosemicarbazones.

Bahauddin Zakariya University