PMID

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Article Title

Organization

Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization.

Shandong University

Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.

Icahn School of Medicine At Mount Sinai

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.

University of Toronto

Discovery and structure-activity analysis of 4-((5-nitropyrimidin-4-yl)amino)benzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors.

Sichuan University

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.

Epizyme

Diamidine compounds for selective inhibition of protein arginine methyltransferase 1.

The University of Georgia

Synthesis and evaluation of carbocyanine dyes as PRMT inhibitors and imaging agents.

Georgia State University

Discovery and mechanistic study of a class of protein arginine methylation inhibitors.

Georgia State University

Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach.

Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire

Fascinating Transformation of SAM-Competitive Protein Methyltransferase Inhibitors from Nucleoside Analogues to Non-Nucleoside Analogues.

Csir-Indian Institute of Chemical Biology

Allosteric Modulation: Dynamics is Double-"E"dged.

Chinese Academy of Sciences

A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6.

Icahn School of Medicine At Mount Sinai

Pharmacophore-based screening of diamidine small molecule inhibitors for protein arginine methyltransferases.

University of Georgia

Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.

University of Toronto

Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation.

Shanghai Institute of Materia Medica

Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.

Chinese Academy of Sciences

Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor.

Icahn School of Medicine At Mount Sinai

Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.

Zhejiang Sci-Tech University