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12 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.EBI
Universit£
Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.EBI
Fudan University
Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship.EBI
University of Hamburg
Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors.EBI
Kyoto University
Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors.EBI
Kyoto University
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression.EBI
East China University of Science and Technology
Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease.EBI
Chinese Academy of Medical Sciences and Peking Union Medical College
In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor.EBI
Universidade De £Vora
N-allyl analogues of phencyclidine: chemical synthesis and pharmacological properties.EBI
TBA
Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives.EBI
Universidade Federal Do Rio Grande Do Sul
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.EBI
University of Ljubljana