BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.2M Compounds and 9.3K Targets. Of those, 1,352K data for 627K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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6 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.EBI
Abbott Laboratories
Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain.EBI
Abbott Laboratories
Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.EBI
Abbott Laboratories
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.EBI
Abbott Laboratories
Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform NaEBI
Siteone Therapeutics
The discovery of benzoxazine sulfonamide inhibitors of NaEBI
Amgen