PMID

Data

Article Title

Organization

Species-dependent uptake of glycylsarcosine but not oseltamivir in Pichia pastoris expressing the rat, mouse, and human intestinal peptide transporter PEPT1.

University of Michigan

Interaction of human organic anion transporters with various cephalosporin antibiotics.

Kyorin University

Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters.

Kyorin University

Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.

Tokyo Women'S Medical University

Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1.

University of Arizona

Interaction of cysteine conjugates with human and rabbit organic anion transporter 1.

University of Arizona

Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.

Gilead Sciences

Interactions of human organic anion as well as cation transporters with indoxyl sulfate.

Nagoya University School of Medicine

The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1.

Medical University of South Carolina

Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

Kyorin University

Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).

University of California

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonists: from bench to bedside.

Novartis Pharma

Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.

Bristol-Myers Squibb

Discovery of novel verinurad analogs as dual inhibitors of URAT1 and GLUT9 with improved Druggability for the treatment of hyperuricemia.

Southern Medical University

Discovery of (

Bristol-Myers Squibb

Discovery of indoximod prodrugs and characterization of clinical candidate NLG802.

Newlink Genetics

Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.

Hemoshear Therapeutics

Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.

TBA

Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.

Pfizer

Pharmacological urate-lowering approaches in chronic kidney disease.

West China Hospital of Sichuan University

Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3.

Tianjin University

Synthesis, pharmacological evaluation, and mechanistic study of adefovir mixed phosphonate derivatives bearing cholic acid and l-amino acid moieties for the treatment of HBV.

Guizhou Medical University

Characterization of ochratoxin A transport by human organic anion transporters.

Kyorin University

Urate transport via human PAH transporter hOAT1 and its gene structure.

Jikei University School of Medicine

Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1.

Gilead Sciences