30 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase.
Astrazeneca
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
Piramal Healthcare
Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.
Chulabhorn Institute
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.
University of Antwerp
Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa.
Universit£
Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill).
Institute For Natural Product Research and Infection Biology
Novel 3-O-acyl mesquitol analogues as free-radical scavengers and enzyme inhibitors: synthesis, biological evaluation and structure-activity relationship.
Institute of Chemical Technology
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors.
Genkyotex
Antioxidant xanthone derivatives induce cell cycle arrest and apoptosis and enhance cell death induced by cisplatin in NTUB1 cells associated with ROS.
Kaohsiung Medical University
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis.
Genkyotex
Glutarimide alkaloids and a terpenoid benzoquinone from Cordia globifera.
Chulabhorn Research Institute
Chemical constituents from the aerial parts of Artemisia minor.
Chinese Academy of Sciences
Insights into the inhibition of xanthine oxidase by curcumin.
Shandong University of Technology
Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage.
Pharmacy School of Wenzhou Medical College
ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity.
Amorepacific
Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2',5'-dialkoxylchalcones as cancer chemopreventive agents.
Kaohsiung Medical University
Phloroglucinols with antioxidant activity and xanthonolignoids from the heartwood of Hypericum geminiflorum.
Kaohsiung Medical University
Schiff base transition metal complexes as novel inhibitors of xanthine oxidase.
Nanjing University
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors.
Universidade Do Minho
An apigenin-derived xanthine oxidase inhibitor from Palhinhaea cernua.
Nanjing University
Free-radical-scavenging and xanthine oxidase inhibitory constituents from Stereospermum personatum.
Institute of Chemical Technology
Structural revision of aspernigrin A, reisolated from Cladosporium herbarum IFB-E002.
Nanjing University
Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata.
Università
New guaianolides and xanthine oxidase inhibitory flavonols from ajania fruticulosa
Nanjing University
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
Institute of Biological Chemistry and The Genomics Research Center
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition.
Università
Synthesis and biological evaluation of new imidazole, pyrimidine, and purine derivatives and analogs as inhibitors of xanthine oxidase.
Università