23 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Multitarget drug discovery for tuberculosis and other infectious diseases.
University of Illinois At Urbana-Champaign
Head-to-head prenyl tranferases: anti-infective drug targets.
University of Illinois At Urbana-Champaign
Kinetic characterization of squalene synthase from Trypanosoma cruzi: selective inhibition by quinuclidine derivatives.
Instituto De Parasitolog£A Y Biomedicina&Quot;L£Pez-Neyra
Synthesis and biological activity of J-104,118, a novel, potent inhibitor of squalene synthase
TBA
The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety.
TBA
Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors.
Bayer Pharma
Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors.
Bayer Pharma
Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors.
Daiichi Sankyo
Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.
University of Illinois At Urbana-Champaign
Synthesis of triphosphonate analogues of farnesyl pyrophosphate. Inhibitors of squalene synthase and protein:farnesyl transferase
TBA
J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogs
TBA
Synthesis of novel monocyclic squalestatin analogues as potential inhibitors of squalene synthase
TBA
Semi-synthetic qualestatins: Squalene synthase inhibition and antifungal activity. The SAR of C6 and C7 modifications
TBA
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.
University of Illinois At Urbana-Champaign
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.
Instituto Venezolano De Investigaciones CientíFicas
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
University of Illinois At Urbana-Champaign
Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis.
Takeda Chemical Industries
Structure-activity relationships of C1 and C6 side chains of zaragozic acid A derivatives.
Merck Research Laboratories