PMID

Data

Article Title

Organization

Solid-phase synthesis of benzisothiazolones as serine protease inhibitors.

Bristol-Myers Squibb Pharmaceutical Research Institute

Discovery of non-competitive thrombin inhibitor derived from competitive tryptase inhibitor skeleton: Shift in molecular recognition resulted from skeletal conversion of carboxylate into phosphonate.

Tokyo University of Pharmacy and Life Sciences

Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.

The Bristol-Myers Squibb Pharmaceutical Research Institute

Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase.

The Bristol-Myers Squibb Pharmaceutical Research Institute

Synthesis of potent and selective 2-azepanone inhibitors of human tryptase.

The Bristol-Myers Squibb Pharmaceutical Research Institute

Dibasic inhibitors of human mast cell tryptase. Part 3: identification of a series of potent and selective inhibitors containing the benzamidine functionality.

Axys Pharmaceuticals

Dibasic inhibitors of human mast cell tryptase. Part 2: structure-activity relationships and requirements for potent activity.

Axys Pharmaceuticals

Syntheses and evaluation of amidinobenzofuran derivatives as tryptase inhibitors.

Yoshitomi Pharmaceutical Industries

Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics.

Molecumetics