Binding Database

The following articles (labelled with PubMed ID or TBD) are for your review

PMID

Data

Article Title

Organization

SAH derived potent and selective EZH2 inhibitors.

Pfizer

Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.

University of North Carolina At Chapel Hill

Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors.

University of North Carolina At Chapel Hill

Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2.

TBA

Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.

University of North Carolina At Chapel Hill

New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms.

University College London