48 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Hydrophobic substituents increase the potency of salacinol, a potenta-glucosidase inhibitor from Ayurvedic traditional medicine 'Salacia'.
Kindai University
Synthesis of novel inhibitors ofa-glucosidase based on the benzothiazole skeleton containing benzohydrazide moiety and their molecular docking studies.
Universiti Teknologi Mara (Uitm)
Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.
Leiden University
Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.
Simon Fraser University
Biological properties of D- and L-1-deoxyazasugars.
Toyama Medical and Pharmaceutical University
Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
Hokuriku University
Synthesis and alpha-D-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potential oral antidiabetic agents.
TBA
Selectivity of 3'-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelae.
Simon Fraser University
Probing the active-site requirements of human intestinal N-terminal maltase glucoamylase: the effect of replacing the sulfate moiety by a methyl ether in ponkoranol, a naturally occurringa-glucosidase inhibitor.
Simon Fraser University
Synthesis of a biologically active isomer of kotalanol, a naturally occurring glucosidase inhibitor.
Simon Fraser University
Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation.
Leiden University
Discovery of new anti-diabetic potential agents based on paracetamol incorporating sulfa-drugs: Design, synthesis, α-amylase, and α-glucosidase inhibitors with molecular docking simulation.
Northern Border University
Novel thiosemicarbazide-based β-carboline derivatives as α-glucosidase inhibitors: Synthesis and biological evaluation.
Wuyi University
Evaluation of novel 2-(quinoline-2-ylthio)acetamide derivatives linked to diphenyl-imidazole as α-glucosidase inhibitors: Insights from in silico, in vitro, and in vivo studies on their anti-diabetic properties.
Qom University of Technology
Probing benzenesulfonamide-thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II.
Cairo University
Synthesis of andrographolide derivatives: a new family of alpha-glucosidase inhibitors.
Zhengzhou University
Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives.
Quaid-I-Azam University
Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties.
Texas Southern University
Enzymatic transformation of esculetin as a potent class of α-glucosidase inhibitors.
Korea Atomic Energy Research Institute (KAERI)
Quinazolinone-1,2,3-triazole-acetamide conjugates as potent α-glucosidase inhibitors: synthesis, enzyme inhibition, kinetic analysis, and molecular docking study.
Tehran University of Medical Sciences Tehran Iran
Synthesis and biological evaluation of 2,5-disubstituted furan derivatives containing 1,3-thiazole moiety as potential α-glucosidase inhibitors.
South China Agricultural University
Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species.
Chengdu University
A comprehensive review on xanthone derivatives as α-glucosidase inhibitors.
Polytechnic Institute of Braganca
Current anti-diabetic agents and their molecular targets: A review.
University of Kwazulu-Natal
Research progress of indole compounds with potential antidiabetic activity.
Xi'An Jiaotong University
Semisynthesis, biological activities, and mechanism studies of Mannich base analogues of magnolol/honokiol as potential α-glucosidase inhibitors.
Zhengzhou University
New cycloalkyl[b]thiophenylnicotinamide-based α-glucosidase inhibitors as promising anti-diabetic agents: Synthesis, in silico study, in vitro and in vivo evaluations.
University of Jinan
Studies on the novel alpha-glucosidase inhibitory activity and structure-activity relationships for andrographolide analogues.
Zhengzhou University
Tigliane Diterpenoids with Larvicidal, Antifungal, and α-Glucosidase Inhibitory Activities from
Yunnan University of Chinese Medicine
: A Prolific Source of Bioactive Secondary Metabolites with Therapeutic Potential.
Zhejiang University
trans, trans-2-C-Aryl-3,4-dihydroxypyrrolidines as potent and selective β-glucosidase inhibitors: Pharmacological chaperones for Gaucher disease.
Chinese Academy of Sciences
Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors.
Zhengzhou University
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Central South University
Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis.
Chinese Academy of Sciences
Germacrane sesquiterpenes from leaves of Eupatorium chinense inhibit protein tyrosine phosphatase.
Tohoku Medical and Pharmaceutical University
Dual-Targeting Antiproliferation Hybrids Derived from 1-Deoxynojirimycin and Kaempferol Induce MCF-7 Cell Apoptosis through the Mitochondria-Mediated Pathway.
Jiangsu University of Science and Technology
Synergetic inhibition of genistein and D-glucose on alpha-glucosidase.
Sun Yat-Sen (Zhongshan) University
Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives.
Chinese Academy of Sciences
Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes.
Shiv Nadar University
Elongation of the side chain by linear alkyl groups increases the potency of salacinol, a potent α-glucosidase inhibitor from the Ayurvedic traditional medicine "Salacia," against human intestinal maltase.
Kindai University
Recent advances on synthesis and biological activities of aurones.
Northwest A&F University
N-alkylated nitrogen-in-the-ring sugars: conformational basis of inhibition of glycosidases and HIV-1 replication.
Hokuriku University
Sesterterpenoids, terretonins A-D, and an alkaloid, asterrelenin, from Aspergillus terreus.
The Chinese Academy of Sciences
