BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 745K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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15 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors.EBI
Ewha Womans University
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors.EBI
Genkyotex
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis.EBI
Genkyotex
NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors.EBI
TBA
A closer look at NEBI
Monash University Malaysia
Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors.EBI
University of Pittsburgh
Ethynyl derivativesBDB
Hoffmann-La Roche
Heteroaryl compounds as inhibitors of TYK2, composition and application thereofBDB
Accro Bioscience (HK)
N/O-Linked Degrons and Degronimers for Protein DegradationBDB
C4 Therapeutics
Inhibitors of protein tyrosine phosphatasesBDB
Indiana University Research and Technology
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseasesBDB
Abbvie
Design and synthesis of novel 2-amino-5-hydroxyindole derivatives that inhibit human 5-lipoxygenase.BDB
Friedrich Alexander University Erlangen
Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.BDB
Bristol-Myers Squibb
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.BDB
Universita Degli Studi Di Bari
Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase.BDB
Toronto General Research Institute