The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

19 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
21
Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors.EBI
Academia Sinica
7
Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses.EBI
Academia Sinica
24
Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells.EBI
Academia Sinica
17
Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis.EBI
Academia Sinica
8
Design, synthesis and molecular docking study of α-triazolylsialosides as non-hydrolyzable and potent CD22 ligands.EBI
Academia Sinica
2
Synthesis and biological evaluation of purine-containing butenolides.EBI
Academia Sinica
6
Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.EBI
Academia Sinica
2
Design, synthesis, and structure-activity relationship of novel dinucleotide analogs as agents against herpes and human immunodeficiency viruses.EBI
Academia Sinica
9
Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.EBI
Academia Sinica
3
Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity.EBI
Academia Sinica
65
PDIA4 inhibitors and use thereof for inhibiting β-cell pathogenesis and treating diabetesBDB
Academia Sinica
4
IDURONIDASE STABILIZERS AND USES THEREOFBDB
Academia Sinica
7
POLYHYDROXYLATED INDOLIZIDINE AND PYRROLIZIDINE DERIVATIVES AND USES THEREOFBDB
Academia Sinica
1
Fluorescent Farnesyl Diphosphate Analogue: A Probe To Validate trans-Prenyltransferase Inhibitors.BDB
Academia Sinica
134
Compounds and methods for treating tuberculosis infectionBDB
Academia Sinica
16
Lithocholic acid analogues that inhibit sialyltransferaseBDB
Academia Sinica
4
Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding.BDB
Academia Sinica
16
Stable benzotriazole esters as mechanism-based inactivators of the severe acute respiratory syndrome 3CL protease.BDB
Academia Sinica
6
Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.BDB
Academia Sinica