BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.5K Targets. Of those, 1.6M data for 780K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

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12 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Cmpds
Data
Article Title
Organization
28
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads.EBI
Agios Pharmaceuticals
45
Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous EBI
Agios Pharmaceuticals
14
Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.EBI
Agios Pharmaceuticals
14
Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.EBI
Agios Pharmaceuticals
391
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
206
Therapeutically active compositions and their methods of useBDB
Agios Pharmaceuticals
5
Methods and compositions for cell-proliferation-related disordersBDB
Agios Pharmaceuticals
207
Therapeutically active compositions and their methods of useBDB
Agios Pharmaceuticals
350
Therapeutic compounds and compositionsBDB
Agios Pharmaceuticals
393
Phenyl and pyridinyl substituted piperidines and piperazines as inhibitors of IDH1 mutants and their use in treating cancerBDB
Agios Pharmaceuticals
389
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals
390
Therapeutically active compounds and their methods of useBDB
Agios Pharmaceuticals