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47 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

Article Title
Preparation and receptor binding affinities of cyclic C-terminal neurotensin (8-13) and (9-13) analogues.EBI
Medical University of South Carolina
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CHEBI
Jagiellonian University Medical College
NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids.EBI
University of Regensburg
Mimicking of Arginine by Functionalized N()-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples.EBI
University of Regensburg
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.EBI
Jagiellonian University Medical College
Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues.EBI
University of Montpellier
The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1).EBI
The Scripps Research Institute
Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists.EBI
Novartis Institutes For Biomedical Research
Imidazole-derived agonists for the neurotensin 1 receptor.EBI
Sanford-Burnham Medical Research Institute
Synthesis and evaluation of a (18)F-labeled diarylpyrazole glycoconjugate for the imaging of NTS1-positive tumors.EBI
Friedrich-Alexander University
Discovery of ML314, a Brain Penetrant Non-Peptidic?-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.EBI
Sanford-Burnham Medical Research Institute
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.EBI
Institute of Organic Synthesis
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.EBI
Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential.EBI
H. Lundbeck
Novel insights into GPCR-peptide interactions: mutations in extracellular loop 1, ligand backbone methylations and molecular modeling of neurotensin receptor 1.EBI
Friedrich-Alexander University
Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc.EBI
National Center For Scientific Research Demokritos
Evaluation of lactam-bridged neurotensin analogues adjusting psi(Pro10) close to the experimentally derived bioactive conformation of NT(8-13).EBI
Friedrich-Alexander University
In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues.EBI
Medical University of South Carolina
Novel bioactive and stable neurotensin peptide analogues capable of delivering radiopharmaceuticals and molecular beacons to tumors.EBI
Washington University
Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics.EBI
Friedrich-Alexander University
Spiroindolones, a potent compound class for the treatment of malaria.EBI
Swiss Tropical and Public Health Institute
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.EBI
Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.EBI
Medical University of South Carolina Campus
Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry.EBI
Institute of Radiopharmacy
The identification of neurotensin NTS1 receptor partial agonists through a ligand-based virtual screening approach.EBI
Wyeth Research
UK-73,093: A non-peptide neurotensin receptor antagonistEBI
Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy.EBI
Medical University of South Carolina
Synthesis and applications of polyamine amino acid residues: improving the bioactivity of an analgesic neuropeptide, neurotensin.EBI
University of Utah
The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay.EBI
Research Triangle Institute
Development of disulfide-functionalized peptides covalently binding G protein-coupled receptors.EBI
Friedrich-Alexander Universit£T Erlangen-N£Rnberg
Design, Structural Optimization, and Characterization of the First Selective Macrocyclic Neurotensin Receptor Type 2 Non-opioid Analgesic.EBI
Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.EBI
Vrije Universiteit Brussel
Synthesis of neurotensin(9-13) analogues exhibiting enhanced human neurotensin receptor binding affinities.EBI
Medical University of South Carolina
Discovery of ?-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.EBI
Sanford Burnham Prebys Medical Discovery Institute
Enhanced tumor retention of NTSR1-targeted agents by employing a hydrophilic cysteine cathepsin inhibitor.EBI
University of Nebraska Medical Center
An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling "Bioorthogonal" Peptide Conjugation.EBI
University of Regensburg
Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.EBI
University of Regensburg
Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTSEBI
University of Regensburg
In Search of the Optimal Macrocyclization Site for Neurotensin.EBI
Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8-13).EBI
Identification and biological evaluation of thiazole-based inverse agonists of ROR?t.EBI
Phenex Pharmaceuticals
Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues.EBI
University of Montpellier
Structure-activity relationships of Bacillus cereus and Bacillus anthracis dihydrofolate reductase: toward the identification of new potent drug leads.BDB
University of Connecticut At Storrs