BDBM50354850 BUDESONIDE::US10869929, Compound Budesonide::US11554172, Compound Budesonide::US11760775, Compound Budesonide
SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
InChI Key InChIKey=VOVIALXJUBGFJZ-KWVAZRHASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 31 hits for monomerid = 50354850
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in insect cells after 24 hrs by scintillation proximity as...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen™ Glucocorticoid Receptor Competitor As...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition interleukin-5 in mouse Y16 cells after 48 hrs by WST-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of IL-5 in mouse pro-B Y16 cells after 48 hrs by WST1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of IL5-mediated proliferation of mouse Y16 cells by WST1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.71E+4nMAssay Description:Inhibition of IL-5 in mouse Y16 cells after 48 hrs by WST1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of interleukin-5More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of interleukin-5 in mouse Y16 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of IL-5 in mouse Y16 cells assessed as reduction in cell proliferation after 48 hrs by WST-1 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Displacement of fluormone labelled AL green from rat recombinant His/GST-tagged androgen receptor LBD after 4 to 6 hrs by fluorescence polarization a...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]-aldosterone from N terminal maltose binding protein tagged human mineralocorticoid receptor LBD (726 to 984 residues) expressed ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of fluormone labelled EL Red from human recombinant estrogen receptor alpha after 1 to 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of fluormone labelled EL Red from human recombinant estrogen receptor beta after 1 to 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Displacement of fluormone labelled PL Red from human recombinant progesterone receptor after 1 to 6 hrs ligand by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 5.45E+4nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of mouse IL-5-induced cell proliferation in mouse Y16 cells after 48 hrs by WST-1 assay relative to controlMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80nMAssay Description:Induction of nuclear translocation of human recombinant ProLabel-tagged mineralocorticoid receptor expressed in CHO-K1 cells after 3 hrs by luminesce...More data for this Ligand-Target Pair
Affinity DataEC50: 3.5nMAssay Description:Induction of nuclear translocation of human recombinant ProLabel-tagged glucocorticoid receptor expressed in CHO-K1 cells after 3 hrs by luminescence...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Transrepression of glucocorticoid receptor in human PBMC assessed as inhibition of LPS induced TNF alpha release preincubated for 45 mins followed by...More data for this Ligand-Target Pair
TargetInterleukin-5 receptor subunit alpha(Mus musculus)
Chungnam National University
Curated by ChEMBL
Chungnam National University
Curated by ChEMBL
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:HUT78 cells were cultured in IMEM plus 20% heat inactivated FBS and cell density was maintained between 0.1 to 1.2 million/mL. 786-O cells were cultu...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:To evaluate the ability of novel steroids to bind to the Glucocorticoid Receptor (GR), a cell-free binding assay was performed using a LanthaScreen T...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of mouse IL5-mediated mouse Y16 cell proliferation after 48 hrs by WST1 assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12.4nMAssay Description:Agonist activity at GR in human SW1353 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activityMore data for this Ligand-Target Pair