BDBM50367502 CILASTATIN

SMILES CC1(C)C[C@@H]1C(=O)N\C(=C/CCCCSC[C@H](N)C(O)=O)C(O)=O

InChI Key InChIKey=DHSUYTOATWAVLW-WFVMDLQDSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50367502   

TargetDipeptidase 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataKi:  110nMAssay Description:Inhibitory activity against beta-lactamase renal dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidase 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against beta-lactamase renal dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidase 1(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against beta-lactamase renal dipeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataKi:  2.31E+5nMAssay Description:TP_TRANSPORTER: inhibition of E1S uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataKi:  1.47E+6nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataIC50:  2.55E+6nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataIC50:  2.39E+6nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in rOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataIC50:  2.49E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 22 member 8(Rattus norvegicus)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50367502(CILASTATIN)
Affinity DataIC50:  7.42E+5nMAssay Description:TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed